Approaches and challenges in SARS-CoV-2 vaccine development
Fecha
2020Autor
Dagotto, Gabriel
Yu, Jingyou
Barouch, Dan H.
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Resumen
The explosive spread of SARS-CoV-2 suggests that a vaccine will be required to end this global pandemic.
Progress in SARS-CoV-2 vaccine development to date has been faster than for any other pathogen in history.
Multiple SARS-CoV-2 vaccine candidates have been evaluated in preclinical models and are currently in clinical trials. In this Perspective, we discuss three topics that are critical for SARS-CoV-2 vaccine development:
antigen selection and engineering, preclinical challenge studies in non-human primate models, and immune
correlates of protection.
Palabras clave
SARS-CoV-2; Vaccine developmentEnlace al recurso
https://doi.org/10.1016/j.chom.2020.08.002Colecciones
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