Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19
Date
2020-06-10Author
Satici, Celal
Altunok, Elif Sargin
Calik, Mustafa
Zuhal Cavus
Esatoglu, Sinem Nihal
Metadata
Show full item record
Documentos PDF
Summary in foreign language
Objective
The aim of the study was to analyze the usefulness of CURB-65 and the pneumonia severity index (PSI) in predicting 30-day mortality in patients with COVID-19, and to identify other factors associated with higher mortality.
Methods
A retrospective study was performed in a pandemic hospital in Istanbul, Turkey, which included 681 laboratory-confirmed patients with COVID-19. Data on characteristics, vital signs, and laboratory parameters were recorded from electronic medical records. Receiver operating characteristic analysis was used to quantify the discriminatory abilities of the prognostic scales. Univariate and multivariate logistic regression analyses were performed to identify other predictors of mortality.
Results
Higher CRP levels were associated with an increased risk for mortality (OR: 1.015, 95% CI: 1.008–1.021; p < 0.001). The PSI performed significantly better than CURB-65 (AUC: 0.91, 95% CI: 0.88–0.93 vs AUC: 0.88, 95% CI: 0.85–0.90; p = 0.01), and the addition of CRP levels to PSI did not improve the performance of PSI in predicting mortality (AUC: 0.91, 95% CI: 0.88–0.93 vs AUC: 0.92, 95% CI: 0.89–0.94; p = 0.29).
Conclusion
In a large group of hospitalized patients with COVID-19, we found that PSI performed better than CURB-65 in predicting mortality. Adding CRP levels to PSI did not improve the 30-day mortality prediction.
Palabras clave
Pneumonia; CURB-65; Pneumonia severity index; Prognosis; MortalityCollections
Estadísticas Google Analytics
Comments
Respuesta Comentario Repositorio Expeditio
Gracias por tomarse el tiempo para darnos su opinión.