Clinical features and short-term outcomes of elderly patients with COVID-19
Date
2020-08Author
Li, Ping
Chen, Lulu
Liu, Zheming
Pan, Jinghui
Zhou, Dingyi
Wang, Hui
Gong, Hongyun
Fu, Zhenmin
Song, Qibin
Min, Qian
Ruan, Shasha
Xu, Tangpeng
Cheng, Fan
Li, Xiangpan
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Background
The outbreak of Coronavirus Disease 2019 (COVID-19) has become a global public health emergency.
Methods
204 elderly patients (≥60 years old) diagnosed with COVID-19 in Renmin Hospital of Wuhan University from January 31st to February 20th, 2020 were included in this study. Clinical endpoint was in-hospital death.
Results
Of the 204 patients, hypertension, diabetes, cardiovascular disease, and chronic obstructive pulmonary disease (COPD) were the most common coexisting conditions. 76 patients died in the hospital. Multivariate analysis showed that dyspnea (hazards ratio (HR) 2.2, 95% confidence interval (CI) 1.414–3.517; p < 0.001), older age (HR 1.1, 95% CI 1.070–1.123; p < 0.001), neutrophilia (HR 4.4, 95% CI 1.310–15.061; p = 0.017) and elevated ultrasensitive cardiac troponin I (HR 3.9, 95% CI 1.471–10.433; p = 0.006) were independently associated with death.
Conclusion
Although so far the overall mortality of COVID-19 is relatively low, the mortality of elderly patients is much higher. Early diagnosis and supportive care are of great importance for the elderly patients of COVID-19.
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