Bogotá, Colombia
Rubiano-Buitrago, P.
Duque, F.
Puyana, M.
Ramos, F.A.
Castellanos, L.
2020-04-14T15:51:47Z
2020-04-14T15:51:47Z
2019
https://doi.org/10.1016/j.phytol.2019.01.021
http://hdl.handle.net/20.500.12010/8767
Four new diterpenes, 6-epipachydictyol A (1), 6-epidictyol C (2), dictyol L (3), 18-acetoxy-xenianol (4) and the
known diterpene dictyoxepin (5) were isolated from the Caribbean alga Dictyota pinnatifida. The structures were
deduced by NMR, MS, optical rotation and 3D modeling. Dictyota pinnatifida is a producer of diterpenes with
chemotaxonomic significance of group I (prenylated germacrene and derivatives) and III (Xeniane and derivatives),
this chemotaxonomic analysis concurs with reported phylogenetic data. Dictyol L showed strong inhibition
of Pseudomonas aeruginosa biofilms, better than kojic acid used as control. Dictyoxepin showed mild
inhibition of Escherichia coli biofilms. These results suggest that these diterpenes could be used as potential
controlling agents of bacterial biofilms recurrent in nosocomial infections.
7 páginas
image/jepg
Universidad de Bogotá Jorge Tadeo Lozano
Marine natural products
Xeniane prenylated guaiane
Diterpenes chemotaxonomic significance
Bacterial biofilm inhibitor diterpenes from dictyota pinnatifida collected from the colombian caribbean
Artículo
Algas marinas -- Investigaciones
Plantas marinas -- Investigaciones
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/acceptedVersion
Abierto (Texto Completo)
https://doi.org/10.1016/j.phytol.2019.01.021
instname:Universidad de Bogotá Jorge Tadeo Lozano
reponame:Repositorio Institucional de la Universidad de Bogotá Jorge Tadeo Lozano