Hosomi, Koji
2020-09-15T19:32:17Z
2020-09-15T19:32:17Z
2020
0264-410X
https://doi.org/10.1016/j.vaccine.2020.08.079
http://hdl.handle.net/20.500.12010/13280
Vaccination has contributed greatly to the control of infectious diseases; however, regional and individual differences are occasionally observed in the efficacy of vaccination. As one explanation for these differences, much attention has focused on the intestinal environment constructed by the interaction of diet
and the gut microbiota. The intestinal environment has several physiological effects on the host immune
system, both locally and systemically, and consequently influences the efficacy of vaccination. In this
review, we discuss the impact of the gut microbiota and dietary nutrients on systemic and oral vaccination as well as their applications in various strategies for immunoregulation, including use as vaccine
adjuvants. This information could contribute to establishing methods of personalized vaccination that
would optimize host immunity by changing the gut environment to maximize vaccine effects.
7 páginas
application/pdf
spa
Vaccine
reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
Gut microbiota
Lymphoid-tissue resident commensal
Lymphoid-tissue resident commensal bacteria
Alcaligenes
Fatty acid
Vitamin
IgA antibody
Impact of the intestinal environment on the immune responses to vaccination
Artículo
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/acceptedVersion
Abierto (Texto Completo)
https://doi.org/10.1016/j.vaccine.2020.08.079
http://purl.org/coar/resource_type/c_2df8fbb1