Basil, Maria C.
Katzen, Jeremy
Engler, Anna E.
Guo, Minzhe
Herriges, Michael J.
Kathiriya, Jaymin J.
Windmueller, Rebecca
Ysasi, Alexandra B.
Zacharias, William J.
Chapman, Hal A.
Kotton, Darrell N.
Rock, Jason R.
Snoeck, Hans Willem
Vunjak-Novakovic, Gordana
Whitsett, Jeffrey A.
Morrisey, Edward E.
2020-07-16T03:42:54Z
2020-07-16T03:42:54Z
2020-04-02
1934-5909
https://www.sciencedirect.com/science/article/pii/S1934590920301016
http://hdl.handle.net/20.500.12010/10630
21 páginas
application/pdf
Science Direct
reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
Reparación Pulmonar
Regeneración Pulmonar
The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future
Artículo
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/acceptedVersion
Lung Repair
Lung Regeneration
https://doi.org/10.1016/j.stem.2020.03.009
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange. In this review and as members of the NIH/NHLBI-supported Progenitor Cell Translational Consortium, we discuss key aspects of lung repair and regeneration. We focus on the cellular compositions within functional niches, cell-cell signaling in homeostatic health, the responses to injury, and new methods to study lung repair and regeneration. We also provide future directions for an improved understanding of the cell biology of the respiratory system, as well as new therapeutic avenues.