Neural and Synaptic Defects in Autism Spectrum Disorders

Wang, Hansen; Doering, Laurie C.

doi:10.3389/978-2-88919-628-9

Neural and Synaptic Defects in Autism Spectrum Disorders

dc.creator	Wang, Hansen
dc.creator	Doering, Laurie C.
dc.date.accessioned	2020-10-13T23:54:40Z
dc.date.available	2020-10-13T23:54:40Z
dc.date.created	2015
dc.description.abstractenglish	Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.	spa
dc.format.extent	287 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	10.3389/978-2-88919-628-9
dc.identifier.isbn	978-2-889-19628-9
dc.identifier.issn	1664-8714
dc.identifier.other	https://www.frontiersin.org/research-topics/1273/neural-and-synaptic-defects-in-autism-spectrum-disorders
dc.identifier.uri	https://hdl.handle.net/20.500.12010/14446
dc.language.iso	eng	spa
dc.publisher	Frontiers Media SA	spa
dc.relation.references	Wang, H., Doering, L. C., eds. (2015). Neural and Synaptic Defects in Autism Spectrum Disorders. Lausanne: Frontiers Media. doi: 10.3389/978-2-88919-628-9
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.rights.creativecommons	https://creativecommons.org/licenses/by/4.0/legalcode
dc.rights.local	Abierto (Texto Completo)	spa
dc.subject	Neurología	spa
dc.subject.lemb	Trastornos del espectro autista	spa
dc.subject.lemb	Síndrome de Rett	spa
dc.subject.lemb	Déficits sinápticos	spa
dc.title	Neural and Synaptic Defects in Autism Spectrum Disorders	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2f33	spa
dc.type.local	Libro	spa

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Facultad de Ciencias Naturales e Ingeniería