Signalling Pathways in Embryonic Development

Sanz Ezquerro, Juan J.; Munsterberg, Andrea E.; Stricker, Sigmar

doi:10.3389/978-2-88945-318-4

Signalling Pathways in Embryonic Development

dc.creator	Sanz Ezquerro, Juan J.
dc.creator	Munsterberg, Andrea E.
dc.creator	Stricker, Sigmar
dc.date.accessioned	2020-10-10T22:24:47Z
dc.date.available	2020-10-10T22:24:47Z
dc.date.created	2018-02-27
dc.description.abstractenglish	The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic “Signalling pathways in embryonic development” has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches.	spa
dc.format.extent	179 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	10.3389/978-2-88945-318-4
dc.identifier.isbn	978-2-889-45318-4
dc.identifier.issn	1664-8714
dc.identifier.other	https://www.frontiersin.org/research-topics/3607/organogenesis-from-development-to-disease
dc.identifier.uri	https://hdl.handle.net/20.500.12010/14351
dc.language.iso	eng	spa
dc.publisher	Frontiers Media SA	spa
dc.relation.references	Sanz-Ezquerro, J. J., Münsterberg, A. E., Stricker, S., eds. (2017). Signalling Pathways in Embryonic Development. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-346-7
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.rights.creativecommons	https://creativecommons.org/licenses/by/4.0/legalcode
dc.rights.local	Abierto (Texto Completo)	spa
dc.subject	Biología	spa
dc.subject.lemb	Desarrollo embrionario	spa
dc.subject.lemb	Embrión	spa
dc.title	Signalling Pathways in Embryonic Development	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2f33	spa
dc.type.local	Libro	spa

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Facultad de Ciencias Naturales e Ingeniería