Organogenesis From Development to Disease

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dc.creatorSunder, Sims Lucas
dc.creatorGood, Misty
dc.creatorVainio, Seppo
dc.date.accessioned2020-10-10T22:18:39Z
dc.date.available2020-10-10T22:18:39Z
dc.date.created2018-11-16
dc.description.abstractenglishDuring embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slight malformations of the organs can cause developmental reprogramming and increase the likelihood of adult onset diseases. The use of experimental animals with genetic mutations that mimic many human conditions has lead to significant scientific advancement of these complex and multifaceted diseases. Furthermore, the utilization of organ culture systems has made for profound insights into the formation of organs. Over recent years, the technology related to molecular profiling and imaging of developing organs has dramatically improved, leading to the identification of subtle genetic and phenotypic alterations. This research topic will focus on the area of organ formation and modeling of human developmental diseases.spa
dc.format.extent112 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.3389/fcell.2017.00085
dc.identifier.isbn978-2-889-45318-4
dc.identifier.issn1664-8714
dc.identifier.otherhttps://www.frontiersin.org/research-topics/3607/organogenesis-from-development-to-disease
dc.identifier.urihttps://hdl.handle.net/20.500.12010/14350
dc.language.isoengspa
dc.publisherFrontiers Media SAspa
dc.relation.referencesSims-Lucas, S., Good, M., Vainio, S., eds. (2017). Organogenesis: From Development to Disease. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-318-4
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/legalcode
dc.rights.localAbierto (Texto Completo)spa
dc.subjectCienciaspa
dc.subject.keywordKidney developmentspa
dc.subject.keywordDiabetes Mellitusspa
dc.subject.lembDevelopmental biology biología del desarrollospa
dc.subject.lembDesarrollo renalspa
dc.subject.lembInflamaciónspa
dc.subject.lembEnfermedad intestinalspa
dc.titleOrganogenesis From Development to Diseasespa
dc.type.coarhttp://purl.org/coar/resource_type/c_2f33spa
dc.type.localLibrospa

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