Nebulized Lidocaine in COVID-19, An Hypothesis

Ali, Ziad A.; El-Mallakh, Rif S.

doi:https://doi.org/10.1016/j.mehy.2020.109947

Nebulized Lidocaine in COVID-19, An Hypothesis

dc.creator	Ali, Ziad A.
dc.creator	El-Mallakh, Rif S.
dc.date.accessioned	2020-07-15T19:56:23Z
dc.date.available	2020-07-15T19:56:23Z
dc.date.created	2020-11
dc.description.abstractenglish	Coronavirus Diseases-2019 (COVID-19) has caused a large global outbreak and has been declared as a pandemic by the World Health Organization (WHO). It has been proposed that COVID-19-related hyperinflammation and dysregulated immune response might play a critical role in developing a cytokine storm which usually progresses to a life-threatening acute lung injury or acute respiratory distress syndrome in infected individuals. Lidocaine, a local analgesic and anti-arrhythmic, is known for its anti-inflammatory actions and has been used to reduce cough and improve respiratory symptoms in severe asthmatic patients. It has a demonstrated safety profile. It is proposed that nebulized lidocaine might be beneficial in reducing cytokines, protecting patients’ lungs and improving outcomes in COVID-19 patients when administered via inhalation as an adjunctive treatment for severe respiratory symptoms in patients fighting the novel Coronavirus. Additional investigation is warranted.	spa
dc.format.extent	3 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	https://doi.org/10.1016/j.mehy.2020.109947	spa
dc.identifier.issn	0306-9877	spa
dc.identifier.other	https://www.sciencedirect.com/science/article/pii/S0306987720312937?via%3Dihub	spa
dc.identifier.uri	https://hdl.handle.net/20.500.12010/10583
dc.publisher	Science Direct	eng
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.source	reponame:Expeditio Repositorio Institucional UJTL	spa
dc.source	instname:Universidad de Bogotá Jorge Tadeo Lozano	spa
dc.subject	Lidocaína	spa
dc.subject.keyword	Lidocaine	spa
dc.subject.keyword	COVID-19	spa
dc.subject.keyword	SARS-CoV-2	spa
dc.subject.keyword	Cytokine-storm	spa
dc.subject.keyword	Anti-inflammatories	spa
dc.subject.lemb	Síndrome respiratorio agudo grave	spa
dc.subject.lemb	COVID-19	spa
dc.subject.lemb	SARS-CoV-2	spa
dc.subject.lemb	Coronavirus	spa
dc.title	Nebulized Lidocaine in COVID-19, An Hypothesis	spa
dc.type.hasversion	info:eu-repo/semantics/acceptedVersion	spa
dc.type.local	Artículo	spa

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