Plausible mechanisms of Niclosamide as an antiviral agent against COVID-19

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dc.creatorPindiprolu, Sai Kiran S.S.
dc.creatorPindiprolu, Sai Harshini
dc.date.accessioned2020-07-15T20:52:51Z
dc.date.available2020-07-15T20:52:51Z
dc.date.created2020-07
dc.description.abstractenglishCorona virus disease 2019 (COVID-19) pandemic caused 18 440 deaths world wide as of 25 March 2020 and posing a serious threat to public health. There is a need, therefore, for effective therapeutic strategies to cure this disease. However, high attrition rates, substantial costs and slow pace are the major limitations of novel drug discovery. Drug repurposing, by employing ‘old’ drugs to treat ‘new’ diseases is an attractive approach in drug discovery. Niclosamide (NIC) is an approved anti-helminthic drug with diverse antiviral mechanisms. In this work we hypothesize, the potential antiviral mechanisms of NIC against COVID-19.spa
dc.format.extent2 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1016/j.mehy.2020.109765spa
dc.identifier.issn0306-9877spa
dc.identifier.otherhttps://www.sciencedirect.com/science/article/pii/S0306987720305892?via%3Dihubspa
dc.identifier.urihttps://hdl.handle.net/20.500.12010/10602
dc.publisherScience Directeng
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectDescubrimiento de medicamentospa
dc.subjectReutilizandospa
dc.subjectNiclosamidaspa
dc.subject.keywordCOVID-19spa
dc.subject.keywordSARS-CoV-2spa
dc.subject.keywordDrug discoveryspa
dc.subject.keywordRepurposingspa
dc.subject.keywordNiclosamidespa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.titlePlausible mechanisms of Niclosamide as an antiviral agent against COVID-19spa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localArtículospa

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