Deceiving SARS-CoV-2 molecular-tropism clues – A combinational contemporary strategy
| dc.creator | Balaji, APB | |
| dc.creator | Bhuvaneswari, Srinivasan | |
| dc.creator | Nanda Kumar, D | |
| dc.date.accessioned | 2020-08-21T19:27:08Z | |
| dc.date.available | 2020-08-21T19:27:08Z | |
| dc.date.created | 2020 | |
| dc.description.abstract | Several attempts to control the dreadfulness of SARS-CoV-2 are still underway. Based on the literature evidences we have speculated a prospective contemporary remedy, which was categorized into Specificity, Remedy, and a Conveyor. In which, pros and cons were discussed and inferred the possible alternatives. (a) Specificity: Implicit to express the ACE2 receptors in conveyor cells to deceive SARS-CoV-2 from prepone targets. (b) Remedy: As depletion of pulmonary surfactants causes strong acute respiratory distress syndrome, we propose an entity of a cost-effective artificial surfactant system as a remedy to pulmonary complications. (c) Conveyor: We propose red blood cells (RBCs) as a conveyor with embedded artificial surfactant and protruding ACE2 receptors for the target-specific delivery. Overall we postulate focused insights by employing a combinational contemporary strategy to steer towards a prospective direction on combating SARS-CoV-2. | spa |
| dc.format.extent | 3 páginas | spa |
| dc.format.mimetype | image/jepg | spa |
| dc.identifier.doi | https://doi.org/10.1016/j.mehy.2020.109976 | spa |
| dc.identifier.issn | 0306-9877 | spa |
| dc.identifier.other | https://doi.org/10.1016/j.mehy.2020.109976 | spa |
| dc.identifier.uri | https://hdl.handle.net/20.500.12010/12102 | |
| dc.language.iso | eng | spa |
| dc.publisher | Medical Hypotheses | spa |
| dc.rights.accessrights | info:eu-repo/semantics/embargoedAccess | spa |
| dc.rights.local | Acceso restringido | spa |
| dc.source | reponame:Expeditio Repositorio Institucional UJTL | spa |
| dc.source | instname:Universidad de Bogotá Jorge Tadeo Lozano | spa |
| dc.subject | SARS-CoV-2 | spa |
| dc.subject | COVID-19 | spa |
| dc.subject | Coronavirus | spa |
| dc.subject | ACE2 receptors | spa |
| dc.subject | Pulmonary surfactant | spa |
| dc.subject | Molecular tropism | spa |
| dc.subject | ARDS | spa |
| dc.subject.lemb | Síndrome respiratorio agudo grave | spa |
| dc.subject.lemb | COVID-19 | spa |
| dc.subject.lemb | SARS-CoV-2 | spa |
| dc.subject.lemb | Coronavirus | spa |
| dc.title | Deceiving SARS-CoV-2 molecular-tropism clues – A combinational contemporary strategy | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
| dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
| dc.type.local | Artículo | spa |
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