Deceiving SARS-CoV-2 molecular-tropism clues – A combinational contemporary strategy

dc.creatorBalaji, APB
dc.creatorBhuvaneswari, Srinivasan
dc.creatorNanda Kumar, D
dc.date.accessioned2020-08-21T19:27:08Z
dc.date.available2020-08-21T19:27:08Z
dc.date.created2020
dc.description.abstractSeveral attempts to control the dreadfulness of SARS-CoV-2 are still underway. Based on the literature evidences we have speculated a prospective contemporary remedy, which was categorized into Specificity, Remedy, and a Conveyor. In which, pros and cons were discussed and inferred the possible alternatives. (a) Specificity: Implicit to express the ACE2 receptors in conveyor cells to deceive SARS-CoV-2 from prepone targets. (b) Remedy: As depletion of pulmonary surfactants causes strong acute respiratory distress syndrome, we propose an entity of a cost-effective artificial surfactant system as a remedy to pulmonary complications. (c) Conveyor: We propose red blood cells (RBCs) as a conveyor with embedded artificial surfactant and protruding ACE2 receptors for the target-specific delivery. Overall we postulate focused insights by employing a combinational contemporary strategy to steer towards a prospective direction on combating SARS-CoV-2.spa
dc.format.extent3 páginasspa
dc.format.mimetypeimage/jepgspa
dc.identifier.doihttps://doi.org/10.1016/j.mehy.2020.109976spa
dc.identifier.issn0306-9877spa
dc.identifier.otherhttps://doi.org/10.1016/j.mehy.2020.109976spa
dc.identifier.urihttps://hdl.handle.net/20.500.12010/12102
dc.language.isoengspa
dc.publisherMedical Hypothesesspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.rights.localAcceso restringidospa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectSARS-CoV-2spa
dc.subjectCOVID-19spa
dc.subjectCoronavirusspa
dc.subjectACE2 receptorsspa
dc.subjectPulmonary surfactantspa
dc.subjectMolecular tropismspa
dc.subjectARDSspa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.titleDeceiving SARS-CoV-2 molecular-tropism clues – A combinational contemporary strategyspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localArtículospa

Archivos

Bloque original

Mostrando 1 - 2 de 2
Cargando...
Miniatura
Nombre:
Captura.PNG
Tamaño:
127.87 KB
Formato:
Portable Network Graphics
Descripción:
Ver portada
Cargando...
Miniatura
Nombre:
Deceiving-SARS-CoV-2-molecular-tropism-clues---A-combinati_2020_Medical-Hypo.pdf
Tamaño:
490.75 KB
Formato:
Adobe Portable Document Format
Descripción:
Artículo reservado

Bloque de licencias

Mostrando 1 - 1 de 1
Cargando...
Miniatura
Nombre:
license.txt
Tamaño:
2.87 KB
Formato:
Item-specific license agreed upon to submission
Descripción: