Immunological deficiencies: more frequent than they seem to be

Douglas Paes Barreto, Irma Cecília; Paes Barreto, Bruno Acatauassú; Gomes do Nascimento Cavalcante, Erica; Condino Neto, Antonio

doi:https://doi.org/10.1016/j.jped.2020.10.009

Immunological deficiencies: more frequent than they seem to be

dc.creator	Douglas Paes Barreto, Irma Cecília
dc.creator	Paes Barreto, Bruno Acatauassú
dc.creator	Gomes do Nascimento Cavalcante, Erica
dc.creator	Condino Neto, Antonio
dc.date.accessioned	2020-11-24T20:31:13Z
dc.date.available	2020-11-24T20:31:13Z
dc.date.created	2020
dc.description.abstractenglish	Objective: A review article was carried out, addressing the clinical and epidemiological characteristics of immune system deficiencies, which are associated with or predispose to recurrent infectious processes, autoimmune diseases, auto inflammatory diseases, or neoplasms, and which are classified as inborn errors of immunity (IEI) and secondary immunodeficiencies (SID). Emphasis was placed on the classification of the main signs and symptoms for each organ and system, which will serve as warning signs, to guide the pediatrician in the investigation of the main IEI. In addition, the main secondary changes in the immune system triggered by infections (with emphasis on COVID-19), drugs, chronic diseases, metabolic and nutritional disorders were identified. Sources of data: This review included articles published in the last five years and that were identified in the MEDLINE platform (PubMed). Summary of findings: The recurrence of infectious processes, associated with the severity of the condition and/or unusual profile of the infectious agent, always related to the age range of symptom onset, are the most important findings for suspected diagnosis.	spa
dc.format.extent	10 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	https://doi.org/10.1016/j.jped.2020.10.009	spa
dc.identifier.issn	0021-7557	spa
dc.identifier.other	https://doi.org/10.1016/j.jped.2020.10.009	spa
dc.identifier.uri	https://hdl.handle.net/20.500.12010/16009
dc.language.iso	eng	spa
dc.publisher	Journal de pediatria	spa
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.rights.local	Abierto (Texto Completo)	spa
dc.source	reponame:Expeditio Repositorio Institucional UJTL	spa
dc.source	instname:Universidad de Bogotá Jorge Tadeo Lozano	spa
dc.subject	Primary immunodeficiency disorders	spa
dc.subject	Immunodeficiency disorders	spa
dc.subject	Classification	spa
dc.subject	Epidemiology	spa
dc.subject	COVID-19	spa
dc.subject	SARS-CoV-2	spa
dc.subject.lemb	Síndrome respiratorio agudo grave	spa
dc.subject.lemb	COVID-19	spa
dc.subject.lemb	SARS-CoV-2	spa
dc.subject.lemb	Coronavirus	spa
dc.title	Immunological deficiencies: more frequent than they seem to be	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2df8fbb1	spa
dc.type.hasversion	info:eu-repo/semantics/acceptedVersion	spa
dc.type.local	Artículo	spa

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