The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin
| dc.creator | Xia, Shuai | |
| dc.creator | Lan, Qiaoshuai | |
| dc.creator | Su, Shan | |
| dc.creator | Wang, Xinling | |
| dc.creator | Xu, Wei | |
| dc.creator | Liu, Zezhong | |
| dc.creator | Zhu, Yun | |
| dc.creator | Wang, Qian | |
| dc.creator | Lu, Lu | |
| dc.creator | Jiang, Shibo | |
| dc.date.accessioned | 2020-09-04T14:03:44Z | |
| dc.date.available | 2020-09-04T14:03:44Z | |
| dc.date.created | 2020 | |
| dc.description.abstractenglish | Dear Editor, The rapid spread of SARS-CoV-2 (also known as 2019-nCoV and HCoV-191), a novel lineage B betacoronavirus (βCoV), has caused a global pandemic of coronavirus disease (COVID-19). It has been speculated that RRAR, a unique furin-like cleavage site (FCS) in the spike protein (S), which is absent in other lineage B βCoVs, such as SARS-CoV, is responsible for its high infectivity and transmissibility.2 | spa |
| dc.format.extent | 3 páginas | spa |
| dc.format.mimetype | application/pdf | spa |
| dc.identifier.doi | https://doi.org/10.1038/s41392-020-0184-0 | spa |
| dc.identifier.issn | 2059-3635 | spa |
| dc.identifier.other | https://www.nature.com/articles/s41392-020-0184-0 | spa |
| dc.identifier.uri | https://hdl.handle.net/20.500.12010/12692 | |
| dc.language.iso | eng | spa |
| dc.publisher | signal transduction and targeted therapy | spa |
| dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | spa |
| dc.rights.local | Acceso restringido | spa |
| dc.source | reponame:Expeditio Repositorio Institucional UJTL | spa |
| dc.source | instname:Universidad de Bogotá Jorge Tadeo Lozano | spa |
| dc.subject | trypsin | spa |
| dc.subject | HCoV-191 | spa |
| dc.subject | betacoronavirus (βCoV) | spa |
| dc.subject | transmissibility | spa |
| dc.subject.lemb | Síndrome respiratorio agudo grave | spa |
| dc.subject.lemb | COVID-19 | spa |
| dc.subject.lemb | SARS-CoV-2 | spa |
| dc.subject.lemb | Coronavirus | spa |
| dc.title | The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
| dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
| dc.type.local | Artículo | spa |
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