Approaches and challenges in SARS-CoV-2 vaccine development

Dagotto, Gabriel; Yu, Jingyou; Barouch, Dan H.

doi:https://doi.org/10.1016/j.chom.2020.08.002

Approaches and challenges in SARS-CoV-2 vaccine development

dc.creator	Dagotto, Gabriel
dc.creator	Yu, Jingyou
dc.creator	Barouch, Dan H.
dc.date.accessioned	2020-09-01T20:55:22Z
dc.date.available	2020-09-01T20:55:22Z
dc.date.created	2020
dc.description.abstract	The explosive spread of SARS-CoV-2 suggests that a vaccine will be required to end this global pandemic. Progress in SARS-CoV-2 vaccine development to date has been faster than for any other pathogen in history. Multiple SARS-CoV-2 vaccine candidates have been evaluated in preclinical models and are currently in clinical trials. In this Perspective, we discuss three topics that are critical for SARS-CoV-2 vaccine development: antigen selection and engineering, preclinical challenge studies in non-human primate models, and immune correlates of protection.	spa
dc.format.extent	7 páginas	spa
dc.format.mimetype	image/jepg	spa
dc.identifier.doi	https://doi.org/10.1016/j.chom.2020.08.002	spa
dc.identifier.issn	1931-3128	spa
dc.identifier.other	https://doi.org/10.1016/j.chom.2020.08.002	spa
dc.identifier.uri	https://hdl.handle.net/20.500.12010/12574
dc.language.iso	eng	spa
dc.publisher	Cell Host & Microbe	spa
dc.rights.accessrights	info:eu-repo/semantics/embargoedAccess	spa
dc.rights.local	Acceso restringido	spa
dc.source	reponame:Expeditio Repositorio Institucional UJTL	spa
dc.source	instname:Universidad de Bogotá Jorge Tadeo Lozano	spa
dc.subject	SARS-CoV-2	spa
dc.subject	Vaccine development	spa
dc.subject.lemb	Síndrome respiratorio agudo grave	spa
dc.subject.lemb	COVID-19	spa
dc.subject.lemb	SARS-CoV-2	spa
dc.subject.lemb	Coronavirus	spa
dc.title	Approaches and challenges in SARS-CoV-2 vaccine development	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2df8fbb1	spa
dc.type.hasversion	info:eu-repo/semantics/acceptedVersion	spa
dc.type.local	Artículo	spa

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