Maintaining social contacts: The physiological relevance of organelle interactions

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dc.creatorSilva, Beatriz S.C.
dc.creatorDiGiovanni, Laura
dc.creatorKumar, Rechal
dc.creatorCarmichael, Ruth E.
dc.creatorKim, Peter K.
dc.creatorSchrader, Michael
dc.date.accessioned2020-07-28T19:32:26Z
dc.date.available2020-07-28T19:32:26Z
dc.date.created2020-07-23
dc.description.abstractenglishMembrane-bound organelles in eukaryotic cells form an interactive network to coordinate and facilitate cellular functions. The formation of close contacts, termed “membrane contact sites” (MCSs), represents an intriguing strategy for organelle interaction and coordinated interplay. Emerging research is rapidly revealing new details of MCSs. They represent ubiquitous and diverse structures, which are important for many aspects of cell physiology and homeostasis. Here, we provide a comprehensive overview of the physiological relevance of organelle contacts. We focus on mitochondria, peroxisomes, the Golgi complex and the plasma membrane, and discuss the most recent findings on their interactions with other subcellular organelles and their multiple functions, including membrane contacts with the ER, lipid droplets and the endosomal/lysosomal compartment.spa
dc.format.extent74 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1016/j.bbamcr.2020.118800spa
dc.identifier.issn0167-4889spa
dc.identifier.otherhttps://www.sciencedirect.com/science/article/pii/S0167488920301580?via%3Dihub#!spa
dc.identifier.urihttps://hdl.handle.net/20.500.12010/11295
dc.publisherBBA - Molecular Cell Researcheng
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectContactos socialesspa
dc.subject.keywordAcyl-CoA binding domain containing proteinspa
dc.subject.keywordPeroxisomesspa
dc.subject.keywordMitochondriaspa
dc.subject.keywordLipid metabolismspa
dc.subject.keywordMembrane contact sitesspa
dc.subject.keywordFFAT motifspa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.titleMaintaining social contacts: The physiological relevance of organelle interactionsspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localArtículospa

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