Comparative Studies of Energy Homeostasis in Vertebrates

Michel, Maximilian

doi:10.3389/978-2-88945-560-7

Comparative Studies of Energy Homeostasis in Vertebrates

dc.creator	Michel, Maximilian
dc.date.accessioned	2020-10-11T03:50:58Z
dc.date.available	2020-10-11T03:50:58Z
dc.date.created	2018-06-05
dc.description.abstractenglish	Food consumption is centrally and peripherally controlled by a core set of genes. Information on the control of feeding in mammals has blossomed after the identification of obesity genes such as ob, db and agouti whose function is well conserved between rodents and man. While energy homeostasis genes are conserved in all vertebrate species (from fish to amphibians and birds to mammals), less is known about their functional conservation. Some endophenotypes are clearly conserved and have helped utilize the respective strengths of different model species to drive scientific insight. However, the animal kingdom has evolved widespread behavioral adaptations to varying food niches and body sizes. Identifying the mechanisms underlying these differences will allow us to find nodes that can be modulated to ameliorate abnormal states or change growth parameters in all vertebrates, from commercially relevant food species to man. In the past decade, a lot of progress has been made in outlining the comparative basis of energy homeostasis in vertebrates. Here, we would like to present a current overview on the comparative endocrinology of energy homeostasis and its underlying neuroendocrinology with an emphasis on the insight this can give us into a) how and with what constraints energy homeostasis evolved and b) how energy homeostasis can be broken into endophenotypes that are translatable between species from fish to man.	spa
dc.format.extent	188 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	10.3389/978-2-88945-560-7
dc.identifier.isbn	978-2-889-45560-7
dc.identifier.issn	1664-8714
dc.identifier.other	https://www.frontiersin.org/research-topics/4907/comparative-studies-of-energy-homeostasis-in-vertebrates
dc.identifier.uri	https://hdl.handle.net/20.500.12010/14362
dc.language.iso	eng	spa
dc.publisher	Frontiers Media SA	spa
dc.relation.references	Michel, M., ed. (2018). Comparative Studies of Energy Homeostasis in Vertebrates. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-560-7	spa
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.rights.creativecommons	https://creativecommons.org/licenses/by/4.0/legalcode
dc.rights.local	Abierto (Texto Completo)	spa
dc.subject	Biología	spa
dc.subject.keyword	Lipoproteins	spa
dc.subject.lemb	Regulación de la ingesta de alimentos	spa
dc.subject.lemb	Metabolismo de los lípidos	spa
dc.subject.lemb	Fisiología comparativa	spa
dc.title	Comparative Studies of Energy Homeostasis in Vertebrates	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2f33	spa
dc.type.local	Libro	spa

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