Cardiovascular disease and COVID-19

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dc.creatorBansal, Manish
dc.date.accessioned2020-08-24T22:38:00Z
dc.date.available2020-08-24T22:38:00Z
dc.date.created2020-06
dc.description.abstractenglishBackground and aims Many patients with coronavirus disease 2019 (COVID-19) have underlying cardiovascular (CV) disease or develop acute cardiac injury during the course of the illness. Adequate understanding of the interplay between COVID-19 and CV disease is required for optimum management of these patients. Methods A literature search was done using PubMed and Google search engines to prepare a narrative review on this topic. Results Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients. Conclusions Most of the current reports on COVID-19 have only briefly described CV manifestations in these patients. Given the enormous burden posed by this illness and the significant adverse prognostic impact of cardiac involvement, further research is required to understand the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in COVID-19 patients.spa
dc.format.extent4 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1016/j.dsx.2020.03.013spa
dc.identifier.issn1871-4021spa
dc.identifier.otherhttps://www.sciencedirect.com/science/article/pii/S1871402120300539?via%3Dihubspa
dc.identifier.urihttps://hdl.handle.net/20.500.12010/12173
dc.language.isoengspa
dc.publisherDiabetes & Metabolic Syndrome: Clinical Research & Reviewsspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.rights.localAcceso restringidospa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectInfarto de miocardiospa
dc.subjectInsuficiencia cardíacaspa
dc.subject.keywordCoronavirus disease 2019spa
dc.subject.keywordMyocarditisspa
dc.subject.keywordMyocardial infarctionspa
dc.subject.keywordHeart failurespa
dc.subject.keywordCardiogenic shockspa
dc.subject.keywordArrhythmiaspa
dc.subject.keywordCardiac troponinsspa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.titleCardiovascular disease and COVID-19spa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localArtículospa

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