Marine Glycosides

Thomas E. Adrian; Sarabia, Francisco; Cheng Sanchez, Ivan

doi:https://doi.org/10.3390/books978-3-03897-903-6

Marine Glycosides

dc.creator	Thomas E. Adrian
dc.creator	Sarabia, Francisco
dc.creator	Cheng Sanchez, Ivan
dc.date.accessioned	2020-10-28T22:42:35Z
dc.date.available	2020-10-28T22:42:35Z
dc.date.created	2019-05-09
dc.description.abstractenglish	In recent years, there has been a steady increase in the publication of papers on the chemistry, biology, and potential clinical uses of marine glycosides. Indeed, more than half of the papers published in this field are less than a decade old. Glycosides have been isolated from species as diverse as algae, fungi, anthozoans, and echinoderms. Even fish of the genus Pardachirus produce glycosides, which they use as shark repellents.The major interest in these compounds as potential drugs stems from their broad spectrum of biological effects. They have been shown to have antimicrobial, antifungal, anti-inflammatory, immune modulatory, and anticancer effects. The anticancer effects of marine glycosides include cell cycle suppression, the induction of apoptosis, and the inhibition of migration, invasion, and metastasis, as well as antiangiogenesis. Marine glycosides influence membrane permeability and have been shown to influence membrane transport at the molecular level through effects on transport carriers and pumps, as well as effects on ligand-gated and voltage-gated channels. Various marine glycosides have been shown to activate sphingomyelinase and ceramide synthesis, to inhibit topoisomerase activity, receptor tyrosine kinase activity, and multidrug resistance protein activity, and to antagonize eicosanoid receptors.This Special Issue covers the entire scope of marine organism-derived glycosides that are of potential value as pharmaceutical agents or leads. These include, but are not limited to, tetracyclic triterpene glycosides, other triterpene glycosides, steroid glycosides, and glycosides of non-isoprenoid aglycones.	spa
dc.format.extent	266 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	https://doi.org/10.3390/books978-3-03897-903-6
dc.identifier.isbn	978-3-038-97902-9
dc.identifier.isbn	978-3-038-97903-6
dc.identifier.other	https://www.mdpi.com/books/pdfview/book/1283
dc.identifier.uri	https://hdl.handle.net/20.500.12010/15040
dc.language.iso	eng	spa
dc.publisher	MDPI - Multidisciplinary Digital Publishing Institute	spa
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.rights.local	Abierto (Texto Completo)	spa
dc.subject	Glucósidos	spa
dc.subject.lemb	Glucósidos triterpénicos	spa
dc.title	Marine Glycosides	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2f33	spa
dc.type.local	Libro	spa

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Facultad de Ciencias Naturales e Ingeniería