Modeling and Analysis of Signal Transduction Networks

Hahn, Juergen

doi:https://doi.org/10.3390/books978-3-03842-142-9

Modeling and Analysis of Signal Transduction Networks

dc.creator	Hahn, Juergen
dc.date.accessioned	2020-10-13T21:04:28Z
dc.date.available	2020-10-13T21:04:28Z
dc.description.abstractenglish	Biological pathways, such as signaling networks, are a key component of biological systems of each living cell. In fact, malfunctions of signaling pathways are linked to a number of diseases, and components of signaling pathways are used as potential drug targets. Elucidating the dynamic behavior of the components of pathways, and their interactions, is one of the key research areas of systems biology. Biological signaling networks are characterized by a large number of components and an even larger number of parameters describing the network. Furthermore, investigations of signaling networks are characterized by large uncertainties of the network as well as limited availability of data due to expensive and time-consuming experiments. As such, techniques derived from systems analysis, e.g., sensitivity analysis, experimental design, and parameter estimation, are important tools for elucidating the mechanisms involved in signaling networks. This Special Issue contains papers that investigate a variety of different signaling networks via established, as well as newly developed modeling and analysis techniques.	spa
dc.format.extent	234 páginas	spa
dc.format.mimetype	application/pdf	spa
dc.identifier.doi	https://doi.org/10.3390/books978-3-03842-142-9
dc.identifier.isbn	978-3-038-42141-2
dc.identifier.isbn	978-3-038-42142-9
dc.identifier.other	https://www.mdpi.com/books/pdfview/book/186
dc.identifier.uri	https://hdl.handle.net/20.500.12010/14438
dc.language.iso	eng	spa
dc.publisher	MDPI - Multidisciplinary Digital Publishing Institute	spa
dc.rights.accessrights	info:eu-repo/semantics/openAccess	spa
dc.rights.creativecommons	https://creativecommons.org/licenses/by/4.0/legalcode
dc.rights.local	Abierto (Texto Completo)	spa
dc.subject	Análisis de sensibilidad	spa
dc.subject.lemb	Transducción de señales	spa
dc.subject.lemb	Estimación de parámetros	spa
dc.subject.lemb	Diseño experimental	spa
dc.title	Modeling and Analysis of Signal Transduction Networks	spa
dc.type.coar	http://purl.org/coar/resource_type/c_2f33	spa
dc.type.local	Libro	spa

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Facultad de Ciencias Naturales e Ingeniería