Piecewise-constant optimal control strategies for controlling the outbreak of COVID-19 in the Irish population

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Mathematical Biosciences

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We introduce a deterministic SEIR model and fit it to epidemiological data for the COVID-19 outbreak in Ireland. We couple the model to economic considerations — we formulate an optimal control problem in which the cost to the economy of the various non-pharmaceutical interventions is minimized, subject to hospital admissions never exceeding a threshold value corresponding to health-service capacity. Within the framework of the model, the optimal strategy of disease control is revealed to be one of disease suppression, rather than disease mitigation.

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SEIR model, Optimal control, Simulated annealing

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