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dc.coverage.spatialColombiaspa
dc.creatorQuinta, Jairo
dc.creatorBayona, Lina M.
dc.creatorCastellanos, Leonardo
dc.creatorPuyana, Mónica
dc.creatorCamargo, Paola
dc.creatorAristizábal, Fabio
dc.creatorEdwards, Christine
dc.creatorTabudravu, Jioji N.
dc.creatorJaspars, Marcel
dc.creatorRamos, Freddy A.
dc.date.accessioned2020-05-14T20:57:03Z
dc.date.available2020-05-14T20:57:03Z
dc.date.created2014
dc.identifier.otherhttps://doi.org/10.1016/j.bmc.2014.10.039spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/9381
dc.description.abstractMarine benthic cyanobacteria are widely known as a source of toxic and potentially useful compounds. These microorganisms have been studied from many Caribbean locations, which recently include locations in the Colombian Caribbean Sea. In the present study, six lipopeptides named almiramides D to H, together with the known almiramide B are identified from a mat characterized as Oscillatoria nigroviridis collected at the Island of Providence (Colombia, S.W. Caribbean Sea).The most abundant compounds, almiramides B and D were characterized by NMR and HRESIMS, while the structures of the minor compounds almiramides E to H were proposed by the analysis of their HRESIMS and MS2 spectra. Almiramides B and D were tested against six human cell lines including a gingival fibroblast cell line and five human tumor cell lines (A549, MDA-MB231, MCF-7, HeLa and PC3) showing a strong but not selectivespa
dc.format.extent10 páginasspa
dc.format.mimetypeimage/jepgspa
dc.subjectMarine natural productsspa
dc.subjectMarine benthic cyanobacteriaspa
dc.subjectOscillatoria nigroviridisspa
dc.subjectAlmiramidesspa
dc.subjectLipopeptidesspa
dc.subjectToxicity against human cellspa
dc.titleAlmiramide D, cytotoxic peptide from the marine cyanobacterium Oscillatoria nigroviridisspa
dc.type.localArtículospa
dc.subject.lembAgentes ototóxicos -- Investigacionesspa
dc.subject.lembMicroalgas -- Investigacionesspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAbierto (Texto Completo)spa
dc.identifier.repourlhttp://expeditiorepositorio.utadeo.edu.cospa
dc.identifier.doihttps://doi.org/10.1016/j.bmc.2014.10.039spa
dc.format.rda1 recurso en línea (archivo de texto)spa
dc.description.rdaRequerimientos de sistema: Adobe Acrobat Readerspa
dc.type.driverinfo:eu-repo/semantics/articlespa


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