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Hydroxychloroquine is effective, and consistently so used early, for Covid-19: A systematic review
Introduction
Hydroxychloroquine (HCQ) has shown efficacy against COVID-19 in some but not all studies. We hypothesized that systematic review would show HCQ to be: effective against COVID-19, more effective when used ...
Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis
Background
Among many drugs that hold potential in COVID-19 pandemic, chloroquine (CQ), and its derivative hydroxychloroquine (HCQ) have generated unusual interest. With increasing usage, there has been growing concern ...
Hydroxychloroquine safety outcome within approved therapeutic protocol for COVID-19 outpatients in Saudi Arabia
Background: Global healthcare is challenged following the COVID-19 pandemic, since late
2019. Multiple approaches have been performed to relieve the pressure and support existing
healthcare. The Saudi Arabian Ministry ...
Hydroxychloroquine use in hospitalised patients with COVID-19: An observational matched cohort study
Aim: To assess the efficacy and safety of hydroxychloroquine with or without azithromycin) in
hospitalized adult patients with COVID-19.
Methods: We utilized a hospital based prospective data registry. The primary end ...
A comprehensive strategy for the early treatment of COVID-19 with azithromycin/hydroxychloroquine and/or corticosteroids: Results of a retrospective observational study in the French overseas department of Réunion Island
Background: This study aimed to evaluate the prognosis of COVID-19 patients in Reunion Island, with a
particular focus on the management of patients with hypoxemic pneumonia.
Methods: This retrospective observational ...
Use of hydroxychloroquine and chloroquine in COVID-19: How good is the quality of randomized controlled trials?
Objectives: We critically evaluated the quality of evidence and quality of harms reporting in clincal
trials that recently evaluated the effectiveness of HCQ/CQ in COVID-19.
Study Design and Setting: Scientific databases ...
COVID-19 in a patient with a flare of systemic lupus erythematosus: a rare case- report
This is a rare case-report of a young female with systemic lupus erythematosus and end-stage
kidney disease (on maintenance hemodialysis) who was admitted to our intensive care unit due
to life-threatening COVID-19. The ...
Outcomes of persons with COVID-19 in hospitals with and without standard treatment with (Hydroxy)chloroquine
Objective
To compare survival of subjects with COVID-19 treated in hospitals that either did or did not routinely treat patients with hydroxychloroquine or chloroquine.
Methods
We analysed data of COVID-19 patients ...
Impact of repurposed drugs on the symptomatic COVID-19 patients
An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel
coronavirus capable of causing coronavirus disease 2019 (COVID-19), was declared as a
global public health emergency on January 30, ...