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Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies
The current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the
coronavirus family, after Severe Acute Respiratory Syndrome and Middle East Respiratory
Syndrome. It is an acute infectious disease ...
Strategies and advances in combating COVID-19 in China
Coronavirus disease 2019 (COVID-19)—the third in a series of coronavirus infections—has caused a global public health event in the 21st century, resulting in substantial global morbidity and mortality. Building on its ...
Preventing infectious diseases for healthy ageing: The VITAL public-private partnership project
Prevention of infectious diseases through immunisation of the growing ageing adult population is essential to improve healthy ageing. However, many licenced and recommended vaccines for this age group
show signs of waning ...
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant
concern to public health care worldwide. As of August 19, 2020, more than 22,140,472 people
are infected, and over 781,135 people have died ...
COVID-19 Vaccine: A comprehensive status report
The current COVID-19 pandemic has urged the scientific community internationally to find
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published investigation
mostly on SARS-CoV and to extent on ...
Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) standardized template for collection of key information for benefit-risk assessment of live-attenuated viral vaccines
Several live-attenuated viral vaccine candidates are among the COVID-19 vaccines in development. The
Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) has prepared a standardized template to describe ...
B-cell engineering: A promising approach towards vaccine development for COVID-19
With the number of cases crossing six million (and more than three hundred and seventy thousand deaths)
worldwide, there is a dire need of a vaccine (and repurposing of drugs) for SARS-CoV-2 disease (COVID-19). It
can ...
Transforming vaccine development
The urgency to develop vaccines against Covid-19 is putting pressure on the long and expensive development
timelines that are normally required for development of lifesaving vaccines. There is a unique opportunity to ...
Development of a novel platform of virus-like particle (VLP) based vaccine against coronavirus 2019 (SARS-CoV-2) by exposing of epitopes: an immunoinformatics approach
The emergence of a rapidly spreading and highly infectious COVID-19 outbreak by a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has caused a global pandemic with unprecedented, social and ...