Buscar
Mostrando documentos 21-30 de 33
Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment
COVID-19 pandemic has a high mortality rate and is affecting practically the entire world population. The
leading cause of death is severe acute respiratory syndrome as a consequence of exacerbated inflammatory
response ...
Glycogen synthase kinase (GSK)-3 and the double-strand RNA-dependent kinase, PKR: When two kinases for the common good turn bad
Glycogen synthase kinase (GSK)-3α/β and the double-stranded RNA-dependent kinase PKR are two sentinel
kinases that carry-out multiple similar yet distinct functions in both the cytosol and the nucleus. While these
kinases ...
Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID-19-associated cardiovascular complications?
Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has currently led to a global pandemic with millions of
confirmed and increasing cases around the world. ...
Male predisposition to severe COVID-19: Review of evidence and potential therapeutic prospects
The severe form of COVID-19 has significant sex disparities, with high fatalities commonly reported among males
than females. The incidence of COVID-19 has also been higher in males compared with their female counterparts.
This ...
The diverse roles of RIP kinases in host-pathogen interactions
Receptor Interacting Protein Kinases (RIPKs) are cellular signaling molecules that are critical for homeostatic
signaling in both communicable and non-communicable disease processes. In particular, RIPK1, RIPK2, RIPK3
and ...
P53 in the impaired lungs
Our laboratory is focused on investigating the supportive role of P53 towards the maintenance of lung homeostasis. Acute lung injury, acute respiratory distress syndrome, chronic obstructive pulmonary disease, pulmonary ...
Therapeutic promises of ginkgolide A: A literature-based review
Ginkgolide A is a highly active platelet activating factor antagonist cage molecule which was isolated from the
leaves of the Ginkgo biloba L. It is known for its inflammatory and immunological potentials. This review ...