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Thromboinflammation in COVID-19 acute lung injury
Since the initial description in 2019, the novel coronavirus SARS-Cov-2 infection (COVID-19) pandemic
has swept the globe. The most severe form of the disease presents with fever and shortness of breath,
which rapidly ...
Cardiovascular involvement during COVID-19 and clinical implications in elderly patients. A review
SARS-CoV-2 betacoronavirus is responsible for the Corona Virus Disease 2019 (COVID-19) which has relevant
pathogenic implications for the cardiovascular system. Incidence and severity of COVID-19 are higher in the
elderly ...
Gastrointestinal symptoms, pathophysiology, and treatment in COVID-19
The novel coronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has emerged and is responsible for the Coronavirus Disease 20191 global pandemic. Coronaviruses, including SARS-CoV-2, are strongly associated ...
Melatonin potentials against viral infections including COVID-19: Current evidence and new findings
Viral infections are dangerous diseases for human health worldwide, which lead to significant morbidity and
mortality each year. Because of their importance and the lack of effective therapeutic approaches, further attempts ...
Gastrointestinal symptoms associated with COVID-19: impact on the gut microbiome
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the greatest
worldwide pandemic since the 1918 flu. The consequences of the coronavirus disease 2019
(COVID-19) are devastating and represent ...
Granulocyte-targeted therapies for airway diseases
The average respiration rate for an adult is 12–20 breaths per minute, which constantly exposes the lungs to
allergens and harmful particles. As a result, respiratory diseases, which includes asthma, chronic obstructive ...
Candesartan could ameliorate the COVID-19 cytokine storm
Background: Angiotensin receptor blockers (ARBs) reducing inflammation and protecting lung and brain function, could be of therapeutic efficacy in COVID-19 patients.
Methods: Using GSEA, we compared our previous transcriptome ...
Diabetes and metabolic syndrome as risk factors for COVID-19
Background and aims: Clinical evidence exists that patients with diabetes are at higher risk for Coronavirus disease 2019 (COVID-19). We investigated the physiological origins of this clinical observation
linking diabetes ...
SARS-CoV-2 infection and obesity: Common inflammatory and metabolic aspects
Backround and aims: According to the World Obesity Federation, “obesity-related conditions seem to
worsen the effect of Covid-19 (SARS-CoV-2)”; additionally the Centres for Disease Control and Prevention
reported that ...
COVID-19 and cardiovascular consequences: Is the endothelial dysfunction the hardest challenge?
A Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has become a pandemic disease named
Coronavirus Disease-19 (COVID-19) of epochal dimension. The clinical spectrum of COVID-19 is wide, ranging
from asymptomatic ...