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Effect of hydroxychloroquine with or without azithromycin on the mortality of COVID-19 patients: a systematic review and meta-analysis
Background
Hydroxychloroquine or chloroquine with or without azithromycin have been widely promoted to treat COVID-19 following early in vitro antiviral effects against SARS-CoV-2
Objective
The aim of this systematic ...
COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity
The SARS-CoV-2 hyperinflammatory response is associated with high mortality. This hypothesis suggests that a deficiency of nicotinamide adenine dinucleotide
(NAD+) may be the primary factor related to the SARS-Cov-2 disease ...
Impact of obesity on hospitalizations and mortality, due to COVID-19: A systematic review
The aim of the current review was to assess whether there was an association
between obesity and higher levels of hospitalization, poor outcomes and
mortality due to the disease of novel coronavirus (COVID-19). Methodology: ...
Early outcomes after hip fracture surgery in COVID-19 patients in New York City
Introduction: The COVID-19 pandemic has spread globally and placed healthcare systems under substantial
strain. Hip fracture patients represent a high-risk population for severe COVID-19 symptoms, as they are generally ...
COVID-19: How to make between-country comparisons
Background: Different countries have adopted different containment and testing strategies for SARS-CoV2. The difference in testing makes it difficult to compare the effect of different containment strategies.
This study ...
Does poor glucose control increase the severity and mortality in patients with diabetes and COVID-19?
Background and aim: Diabetes in often associated with an increased severity and mortality in patients
with COVID-19. We aimed to find out whether the severity and mortality in patients with diabetes with
COVID-19 has any ...
A call for strengthened evidence on targeted, non-pharmaceutical interventions against COVID-19 for the protection of vulnerable individuals in sub-Saharan Africa
Following the easing of lockdown measures in many sub-Saharan African countries, coronavirus disease
2019 (COVID-19) cases have been on the rise. As the transmission of severe acute respiratory syndrome
coronavirus 2 ...
Socioeconomic inequality in global incidence and mortality rates from COVID-19: an Ecological study
Objective: Coronavirus disease is an infectious disease caused by a newly discovered
coronavirus. Epidemiological and clinical features of patients with COVID-19 have been
examined but Socio-economic aspects of the issue ...
Hypotheses about sub-optimal hydration in the weeks before coronavirus dis‐ ease (COVID-19) as a risk factor for dying from COVID-19
To address urgent need for strategies to limit mortality from coronavirus disease 2019 (COVID-19), this review describes experimental, clinical and epidemiological evidence that suggests that chronic sub-optimal hydration ...
Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19
Significance: The United States is in an acceleration phase of the COVID-19 pandemic. Currently there is no
known effective therapy or vaccine for treatment of SARS-CoV-2, highlighting urgency around identifying
effective ...