Exploring algae and cyanobacteria as a promising Q6 natural source of antiviral drug against SARS-CoV-2
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Abstract
The present outburst of coronavirus-associated (SARS-CoV-2) acute respiratory disease
coronavirus disease 19 (COVID-19) in December 2019 in Wuhan, China is the third recognised spill over due to the zoonotic transmission. SARS-CoVs are about 29.7 kb positive,
single stranded (ss) RNA viruses that are considered as zoonotic pathogens, bat being their
natural reservoirs and also shows transmission within humans. The rapidly increasing
COVID-19 cases and need of best and efficient drug/vaccine/strategy to counteract the virus
entry and its pathogenesis has made it a Herculean challenge for scientists. Synthetic
drugs associated complications has attracted scientific attention for natural product-based
drugs. Chemo-diversity of algae and cyanobacteria offers a novel approach and can be
recognized as a relevant source for developing a future natural “antiviral drug”. The aim of
this review is to highlight important features of SARS-CoV-2/COVID-19 and the antiviral
compounds recognized in algae and cyanobacteria, with their mechanisms of actions.
Algae possess both immunity improving capacity and suppresses many viruses. Thus, they
can be recommended as a preventive and curative remedy against SARS-CoV-2.
Link to resource
https://doi.org/10.1016/j.bj.2020.11.014Collections
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