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dc.creatorPerveen, Nighat
dc.creatorMuzaffar, Sabir Bin
dc.creatorAl-Deeb, Mohammad Ali
dc.date.accessioned2020-12-09T20:32:22Z
dc.date.available2020-12-09T20:32:22Z
dc.date.created2020
dc.identifier.issn1319-562Xspa
dc.identifier.otherhttps://doi.org/10.1016/j.sjbs.2020.11.077spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/16428
dc.description.abstractThe novel coronavirus disease (COVID-19) that emerged in December 2019 had caused substantial morbidity and mortality at the global level within few months. It affected economies, stopped travel, and isolated individuals and populations around the world. Wildlife, especially bats, serve as reservoirs of coronaviruses from which the variant Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) emerged that causes COVID-19. In this review, we describe the current knowledge on COVID-19 and the significance of wildlife hosts in its emergence. Mammalian and avian coronaviruses have diverse host ranges with distinct lineages of coronaviruses. Recombination and reassortments occur more frequently in mixed-animal markets where diverse viral genotypes intermingle. Human coronaviruses have evolved through gene gains and losses primarily in interfaces where wildlife and humans come in frequent contact. There is a gap in our understanding of bats as reservoirs of coronaviruses and there is a misconception that bats periodically transmit coronaviruses to humans. Future research should investigate bat viral diversity and loads at interfaces between humans and bats. Furthermore, there is an urgent need to evaluate viral strains circulating in mixed animal markets, where the coronaviruses circulated before becoming adapted to humans. We propose and discuss a management intervention plan for COVID-19 and raise questions on the suitability of current containment plans. We anticipate that more virulent coronaviruses could emerge unless proper measures are taken to limit interactions between diverse wildlife and humans in wild animal markets.spa
dc.format.extent31 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherSaudi Journal of Biological Sciencesspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectAnimal reservoirspa
dc.subjectCOVID-19spa
dc.subjectInterspecies transmissionspa
dc.subjectMERS-CoVspa
dc.subjectSARS-CoVspa
dc.subjectSARS-CoV-2spa
dc.titleExploring human-animal host interactions and emergence of COVID-19: evo- lutionary and ecological dynamicsspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAbierto (Texto Completo)spa
dc.identifier.doihttps://doi.org/10.1016/j.sjbs.2020.11.077spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa


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