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Preoperative chest computed tomography screening for coronavirus disease 2019 in asymptomatic patients undergoing cardiac surgery
dc.creator | Knol, Wiebe G. | |
dc.creator | Thuijs, Daniel J.F.M. | |
dc.creator | Odink, Arlette E. | |
dc.creator | Maurovich-Horvat, Pal | |
dc.creator | Jong, Pim A. de | |
dc.creator | Krestin, Gabriel P. | |
dc.creator | Bogers, Ad J.J.C. | |
dc.creator | Budde, Ricardo P.J. | |
dc.date.accessioned | 2020-10-21T19:49:39Z | |
dc.date.available | 2020-10-21T19:49:39Z | |
dc.date.created | 2020 | |
dc.identifier.issn | 1043-0679 | spa |
dc.identifier.other | https://doi.org/10.1053/j.semtcvs.2020.09.027 | spa |
dc.identifier.uri | http://hdl.handle.net/20.500.12010/14668 | |
dc.description.abstract | Due to the outbreak of Severe Acute Respiratory Syndrome coronavirus (SARS-Cov-2), an efficient COVID-19 screening strategy is required for patients undergoing cardiac surgery. The objective of this prospective observational study was to evaluate the role of preoperative computed tomography (CT) screening for COVID-19 in a population of COVID-19 asymptomatic patients scheduled for cardiac surgery. Between the 29th of March and the 26th of May 2020, patients asymptomatic for COVID-19 underwent a CT-scan the day before surgery, with reverse-transcriptase polymerase-chain reaction (RT-PCR) reserved for abnormal scan results. The primary endpoint was the prevalence of abnormal scans, which was evaluated using the CO-RADS score, a COVID-19 specific grading system. In a secondary analysis, the rate of abnormal scans was compared between the screening cohort and matched historical controls who underwent routine preoperative CT-screening prior to the SARS-Cov-2 outbreak. Of the 109 patients that underwent CT-screening, an abnormal scan result was observed in 7.3% (95% confidence interval: 3.2 14.0%). One patient, with a normal screening CT, was tested positive for COVID-19, with the first positive RT-PCR on the ninth day after surgery. A rate of preoperative CT-scan abnormalities of 8% (n = 8) was found in the unexposed historical controls (P > 0.999). In asymptomatic patients undergoing cardiac surgery, preoperative screening for COVID-19 using computed tomography will identify pulmonary abnormalities in a small percentage of patients that do not seem to have COVID-19. Depending on the prevalence of COVID-19, this results in an unfavorable positive predictive value of CT screening. Care should be taken when considering CT as a screening tool prior to cardiac surgery. | spa |
dc.format.extent | 8 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | eng | spa |
dc.publisher | Seminars | spa |
dc.source | reponame:Expeditio Repositorio Institucional UJTL | spa |
dc.source | instname:Universidad de Bogotá Jorge Tadeo Lozano | spa |
dc.subject | Coronavirus Disease 2019 | spa |
dc.subject | Patients Undergoing | spa |
dc.subject | Cardiac Surgery | spa |
dc.title | Preoperative chest computed tomography screening for coronavirus disease 2019 in asymptomatic patients undergoing cardiac surgery | spa |
dc.type.local | Artículo | spa |
dc.subject.lemb | Síndrome respiratorio agudo grave | spa |
dc.subject.lemb | COVID-19 | spa |
dc.subject.lemb | SARS-CoV-2 | spa |
dc.subject.lemb | Coronavirus | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
dc.rights.local | Abierto (Texto Completo) | spa |
dc.identifier.doi | https://doi.org/10.1053/j.semtcvs.2020.09.027 | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | spa |
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