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dc.creatorVenugopal, Usha
dc.creatorJilani, Nargis
dc.creatorRabah, Sami
dc.creatorShariff, Masood A.
dc.creatorJawed, Muzamil
dc.creatorMendez Batres, Astrid
dc.creatorAbubacker, Muhamed
dc.creatorMenon, Sharika
dc.creatorPillai, Anjana
dc.creatorShabarek, Nehad
dc.creatorKasubhai, Moiz
dc.creatorDimitrov, Vihren
dc.creatorMenon, Vidya
dc.date.accessioned2020-10-21T17:24:35Z
dc.date.available2020-10-21T17:24:35Z
dc.date.created2020
dc.identifier.issn1201-9712spa
dc.identifier.otherhttps://doi.org/10.1016/j.ijid.2020.10.036spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/14660
dc.description.abstractBackground New York City (NYC) has endured the greatest burden of COVID-19 infections in the US. Health inequities in South Bronx predisposed this community to a greater number of infections cases, hospitalisations and mortality. Health Care Workers (HCWs) are at high-risk of exposure to the infection. This study aims to assess seroprevalence and associated characteristics of consenting HCWs from a NYC public hospital. Methods Cross sectional study including serum samples for qualitative SARS-CoV-2 antibody testing with nasopharyngeal swabs for SARS-CoV-2 PCR and completion of an online survey capturing demographics, COVID-19 symptoms during the preceding months on duty, details of healthcare and community exposure, and travel history were collected from consenting participants in May 2020. Participants’ risk of exposure to COVID-19 infection in hospital and in the community was defined based on CDC guidelines. Travel history to high-risk areas was also considered an additional risk. The Odds Ratio with bivariable and multivariable logistic regression was used to assess characteristics associated with seroprevalence. Results A total of 500 HCW were tested, 137 (27%) tested positive for SARS-CoV-2 antibody. Symptomatic participants had a 75% (98/130) rate of seroconversion compared to those without symptoms. Subjects with anosmia and ageusia had increased odds of seroconversion in comparison to those without these symptoms. Community exposure was 34% (44/130) among those who had positive antibodies. Conclusion Seroprevalence among HCWs was high compared to the community at the epicenter of the pandemic. Further studies to evaluate sustained adaptive immunity in this high-risk group will guide our response to a future surge.spa
dc.format.extent24 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherInternational Journal of Infectious Diseasesspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectSeroprevalencespa
dc.subjectHealth care workersspa
dc.subjectAntibodyspa
dc.subjectExposurespa
dc.subjectSARS-CoV-2 PCRspa
dc.subjectCOVID-19spa
dc.titleSARS-CoV-2 seroprevalence among health care workers in a new york city hospital: A cross-sectional analysis during the COVID-19 pandemicspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAbierto (Texto Completo)spa
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2020.10.036spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa


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