Mostrar el registro sencillo del documento
Clinical characteristics and outcomes among hospitalized adults with severe COVID-19 admitted to a tertiary medical center and receiving antiviral, antimalarials, glucocorticoids, or immunomodulation with tocilizumab or cyclosporine: A retrospective observational study (COQUIMA cohort)
dc.creator | Guisado-Vasco, Pablo | |
dc.creator | Valderas-Ortega, Sofia | |
dc.creator | Carralon-González, Maria Maravillas | |
dc.creator | Roda-Santacruz, Ana | |
dc.creator | Gonzalez-Cortijo, Lucia | |
dc.creator | Sotres-Fernandez, Gabriel | |
dc.creator | Martí-Ballesteros, Eva María | |
dc.creator | Luque-Pinilla, Jose Manuel | |
dc.creator | Almagro-Casado, Elena | |
dc.creator | La Coma-Lanuza, Felix J. | |
dc.creator | Barrena-Puertas, Ruth | |
dc.creator | Malo-Benages, Esteban Javier | |
dc.creator | Monforte-Gómez, María Jose | |
dc.creator | Diez-Munar, Rocío | |
dc.creator | Merino-Lanza, Esther | |
dc.creator | Comeche-Casanova, Lorena | |
dc.creator | Remirez-de-Esparza-Otero, Margarita | |
dc.creator | Correyero-Plaza, María | |
dc.creator | Recio-Rodríguez, Manuel | |
dc.creator | Rodríguez-Lopez, Margarita | |
dc.creator | Andreu-Vazquez, Cristina | |
dc.creator | Thuissard-Vasallo, Israel John | |
dc.creator | Echave-Sustaeta María-Tome, Jose María | |
dc.creator | Carnevali-Ruiz, Daniel | |
dc.date.accessioned | 2020-10-19T17:34:46Z | |
dc.date.available | 2020-10-19T17:34:46Z | |
dc.date.created | 2020 | |
dc.identifier.issn | 2589-5370 | spa |
dc.identifier.other | https://doi.org/10.1016/j.eclinm.2020.100591 | spa |
dc.identifier.uri | http://hdl.handle.net/20.500.12010/14585 | |
dc.description.abstract | Background: The COVID-19 outbreak challenges the Spanish health system since March 2020. Some available therapies (antimalarials, antivirals, biological agents) were grounded on clinical case observations or basic science data. The aim of this study is to describe the characteristics and impact of different therapies on clinical outcomes in a cohort of severe COVID-19 patients. Methods: In this retrospective, single-center, observational study, we collected sequential data on adult patients admitted to Hospital Universitario Quironsalud Madrid. Eligible patients should have a microbiological (positive test on RT-PCR assay from a nasal swab) or an epidemiological diagnosis of severe COVID-19. Demographic, baseline comorbidities, laboratory data, clinical outcomes, and treatments were compared between survivors and non-survivors. We carried out univariate and multivariate logistic regression models to assess potential risk factors for in-hospital mortality. | spa |
dc.format.extent | 10 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | eng | spa |
dc.publisher | EClinical Medicine | spa |
dc.source | reponame:Expeditio Repositorio Institucional UJTL | spa |
dc.source | instname:Universidad de Bogotá Jorge Tadeo Lozano | spa |
dc.subject | Severe COVID-19 | spa |
dc.subject | SARS-CoV-2 infection | spa |
dc.subject | Cyclosporine a | spa |
dc.subject | Acute respiratory insufficiency | spa |
dc.subject | Immunosuppressants | spa |
dc.subject | Hyperinflammation state | spa |
dc.title | Clinical characteristics and outcomes among hospitalized adults with severe COVID-19 admitted to a tertiary medical center and receiving antiviral, antimalarials, glucocorticoids, or immunomodulation with tocilizumab or cyclosporine: A retrospective observational study (COQUIMA cohort) | spa |
dc.type.local | Artículo | spa |
dc.subject.lemb | Síndrome respiratorio agudo grave | spa |
dc.subject.lemb | COVID-19 | spa |
dc.subject.lemb | SARS-CoV-2 | spa |
dc.subject.lemb | Coronavirus | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
dc.rights.local | Abierto (Texto Completo) | spa |
dc.identifier.doi | https://doi.org/10.1016/j.eclinm.2020.100591 | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | spa |
Archivos en el documento
Archivos | Tamaño | Formato | Ver |
---|---|---|---|
No hay archivos asociados a este documento. |