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dc.creatorBrüggemann, Renée R.A.G.
dc.creatorSpaetgens, Bart
dc.creatorGietema, Hester A.
dc.creatorBrouns, Steffie H.A.
dc.creatorStassen, Patricia M.
dc.creatorMagdelijns, Fabienne J.
dc.creatorRennenberg, Roger J.
dc.creatorHenry, Ronald M.A.
dc.creatorMulder, Mark M.G.
dc.creatorBussel, Bas C.T. van
dc.creatorSchnabel, Ronny M.
dc.creatorHorst, Iwan C.C. van der
dc.creatorWildberger, Joachim E.
dc.creatorStehouwer, Coen D.A.
dc.creatorCate, Hugo ten
dc.description.abstractBackground The risk of pulmonary embolism (PE) in patients with Coronavirus Disease 2019 (COVID-19) is recognized. The prevalence of PE in patients with respiratory deterioration at the Emergency Department (ED), the regular ward, and the Intensive Care Unit (ICU) are not well-established. Objectives We aimed to investigate how often PE was present in individuals with COVID-19 and respiratory deterioration in different settings, and whether or not disease severity as measured by CT-severity score (CTSS) was related to the occurrence of PE. Patients/Methods Between April 6th and May 3rd, we enrolled 60 consecutive adult patients with confirmed COVID-19 from the ED, regular ward and ICU who met the pre-specified criteria for respiratory deterioration. Results A total of 24 (24/60: 40% (95%CI: 28-54%)) patients were diagnosed with PE, of whom 6 were in the ED (6/23: 26% (95% CI: 10-46%)), 8 in the regular ward (8/24: 33% (95%CI: 16-55%)), and 10 in the ICU (10/13: 77% (95%CI: 46-95%)). CTSS (per unit) was not associated with the occurrence of PE (age and sex-adjusted OR 1.06 (95%CI 0.98-1.15)). Conclusion The number of PE diagnosis among patients with COVID-19 and respiratory deterioration was high; 26% in the ED, 33% in the regular ward and 77% in the ICU respectively. In our cohort CTSS was not associated with the occurrence of PE. Based on the high number of patients diagnosed with PE among those scanned we recommend a low threshold for performing computed tomography angiography in patients with COVID-19 and respiratory
dc.format.extent22 páginasspa
dc.publisherThrombosis Researchspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCOVID-19 (coronavirus disease 2019)spa
dc.subjectPulmonary embolismspa
dc.subjectComputed tomography angiographyspa
dc.titleThe prevalence of pulmonary embolism in patients with COVID-19 and respiratory decline: A three-setting comparisonspa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.rights.localAbierto (Texto Completo)spa

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