Show simple item record

dc.creatorHenry, Kevin A.
dc.creatorMacKenzie, C. Roger
dc.date.accessioned2020-10-05T22:06:38Z
dc.date.available2020-10-05T22:06:38Z
dc.date.created2018-11-16
dc.identifier.isbn9782889454327
dc.identifier.issn16648714
dc.identifier.otherhttps://www.frontiersin.org/research-topics/5098/single-domain-antibodies-biology-engineering-and-emerging-applications
dc.identifier.urihttp://hdl.handle.net/20.500.12010/14215
dc.format.extent338 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherFrontiers Media SAspa
dc.subjectMedicine (General)spa
dc.subjectAllergy and Immunologyspa
dc.subjectSinglespa
dc.titleSingle-Domain Antibodies: Biology, Engineering and Emerging Applicationsspa
dc.type.localLibrospa
dc.subject.lembDomain antibodyspa
dc.subject.lembAntibody discoveryspa
dc.subject.lembAntibody engineeringspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.localAbierto (Texto Completo)spa
dc.subject.keywordTherapeutic antibodyspa
dc.subject.keywordDiagnostic antibodyspa
dc.identifier.doi10.3389/978-2-88945-432-7
dc.relation.referencesHenry, K. A., MacKenzie, C. R., eds. (2018). Single-Domain Antibodies: Biology, Engineering and Emerging Applications. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-432-7
dc.description.abstractenglishSingle-domain antibodies (sdAbs) represent the minimal antigen binding-competent form of the immunoglobulin domain and have unique properties and applications. SdAbs are naturally produced as the variable domains of the heavy chain-only antibodies of camelid ruminants and cartilaginous fishes, but can also be engineered synthetically from autonomous human or mouse VH or VL domains. The scope of this research topic and associated e-book covers current understanding and new developments in (i) the biology, immunology and immunogenetics of sdAbs in camelids and cartilaginous fishes, (ii) strategies for sdAb discovery, (iii) protein engineering approaches to increase the solubility, stability and antigen-binding affinity of sdAbs and (iv) specialized applications of sdAbs in areas such diagnostics, imaging and therapeutics.spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2f33spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record