COVID-19 outbreak in Jordan: Epidemiological features, clinical characteristics, and laboratory findings
Date
2020Author
Samrah, Shaher M.
Al-Mistarehi, Abdel-Hameed W.
Ibnian, Ali M.
Raffee, Liqaa A.
Momany, Suleiman M.
Al-Ali, Musa
Hayajneh, Wail A.
Yusef, Dawood H.
Awad, Samah M.
Khassawneh, Basheer Y.
Metadata
Show full item recordAbstract
Background: In March 2020, an outbreak of coronavirus 19 (COVID-19) was detected in the North of Jordan.
This retrospective study is the first from Jordan to report the epidemiologic, clinical, laboratory, and radiologic
characteristics of COVID-19 infected patients.
Methods: All patients with laboratory-confirmed COVID-19 infection by RT-PCR in the North of Jordan admitted
between March 15 and April 2, 2020 were included. The clinical features, radiological, and laboratory findings
were reviewed.
Results: Of 81 patients affected, 79 (97.5%) shared a common exposure to four recent travelers from endemic
areas. The mean age was 40 years. Although about half (44 [54.3%]) were females, symptomatic patients were
mostly females (75%). The most common presenting symptoms were nasal congestion, sore throat and dry
cough. Less than one-third (31%) had chronic diseases. Although 84% of patients reported receiving Bacille
Calmette-Guérin (BCG) vaccination, more asymptomatic patients had BCG than symptomatic (p = 0.017).
Almost all patients (97.5%) had an elevated D-dimer level. Erythrocyte sedimentation rate (ESR) and c-reactive
protein were elevated in 50% and 42.7% of patients, respectively. High ESR found to be the predictor of abnormal chest radiograph observed in 13 (16%) patients with OR of 14.26 (95% CI 1.37–147.97, p = 0.026).
Conclusions: An outbreak of COVID-19 infection in northern Jordan affected more females and relatively young
individuals and caused mainly mild illnesses. The strict outbreak response measures applied at early stages
probably contributed to the lenient nature of this outbreak, but the contribution of other factors to such
variability in COVID-19 presentation is yet to be explained.
Palabras clave
SARS-CoV-2; COVID-19; Coronavirus; c-Reactive protein; Erythrocyte sedimentation rate; BCG; D-dimer; Outbreak; JordanLink to resource
https://doi.org/10.1016/j.amsu.2020.07.020Collections
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