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Changing dynamics of psychoneuroimmunology during the COVID-19 pandemic
dc.creator | Debnath, Monojit | |
dc.creator | Berk, Michael | |
dc.creator | Maes, Michael | |
dc.date.accessioned | 2020-09-28T17:01:13Z | |
dc.date.available | 2020-09-28T17:01:13Z | |
dc.date.created | 2020 | |
dc.identifier.issn | 2666-3546 | spa |
dc.identifier.other | https://doi.org/10.1016/j.bbih.2020.100096 | spa |
dc.identifier.uri | http://hdl.handle.net/20.500.12010/13914 | |
dc.description.abstract | The Coronavirus Disease-2019 (COVID-19) pandemic has led to a global health care crisis. Emerging research suggest an unanticipated impact of COVID-19 on mental and/or psychological health of both the general community and affected individuals. The fear of the COVID-19 epidemic and the consequent lockdown and economic crisis has led to globally increased psychological distress. The biological bases of immediate and new onset of psychiatric symptoms in individuals with COVID-19 are not yet known. COVID-19 infection may lead to activated immune-inflammatory pathways and a cytokine storm. Activated immune-inflammatory pathways, especially chronic low-grade inflammation, are associated with major psychiatric disorders in at least a subset of individuals. We propose that both the (sub)chronic inflammatory response and cytokine storm might crucially be involved in the immediate manifestation of neuropsychiatric symptoms in individuals with COVID-19 infection as well as heightened expression of psychiatric symptoms in COVID-19 infected individuals with prior psychiatric conditions. These events might expand concepts in psychoneuroimmunology, with the importance of chronic-low grade inflammation augmented by the cytokine storm hypothesis. Additionally, this might augment and refine diagnosis and prognostic management as well as treatment. | spa |
dc.format.extent | 3 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | eng | spa |
dc.publisher | Brain, Behavior, & Immunity - Health | spa |
dc.source | reponame:Expeditio Repositorio Institucional UJTL | spa |
dc.source | instname:Universidad de Bogotá Jorge Tadeo Lozano | spa |
dc.subject | COVID-19 | spa |
dc.subject | Chronic low-grade inflammation | spa |
dc.subject | Cytokine storm | spa |
dc.subject | Psychiatry | spa |
dc.subject | Mental health | spa |
dc.subject | Neuroscience | spa |
dc.subject | Psychosis | spa |
dc.subject | Depression | spa |
dc.subject | Delirium | spa |
dc.title | Changing dynamics of psychoneuroimmunology during the COVID-19 pandemic | spa |
dc.type.local | Artículo | spa |
dc.subject.lemb | Síndrome respiratorio agudo grave | spa |
dc.subject.lemb | COVID-19 | spa |
dc.subject.lemb | SARS-CoV-2 | spa |
dc.subject.lemb | Coronavirus | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | spa |
dc.rights.local | Abierto (Texto Completo) | spa |
dc.identifier.doi | https://doi.org/10.1016/j.bbih.2020.100096 | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | spa |
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