Evaluating the massive underreporting and undertesting of COVID-19 cases in multiple global epicenters
Data
2020Autor
Lau, H.
Khosrawipour, T.
Kocbach, P.
Ichii, H.
Bania, J.
Khosrawipour, V.
Metadata
Mostrar registro completoResumo
Background: With continuous global COVID-19 outbreak, differing case numbers and mortality
rates are observed. While actual case numbers appear vague, mortality numbers related to
COVID-19 seem more precise. In this study, we used the mortality rate as the main indicator to
evaluate the extent of underreporting and underdetection of COVID-19 cases.
Methods: We have analyzed all available data provided by the World Health Organization on
the development of international COVID-19 cases and mortality numbers on March 17th, 2020. A
crude case-fatality risk (cCFR) and adjusted case-fatality risk (aCFR) was calculated for China,
South Korea, Japan, Italy, France, Spain, Germany, Iran and the United States. Additionally, a
fold-change (FC) was derived for each country.
Results: The highest aCFR and FC were detected for Spain. Based on their FC values, an
extremely high number of undetected COVID-19 cases was displayed in France, the United
States, Italy and Spain. For these countries, our findings indicate a detection rate of only 1---2%
of total actual COVID-19 cases.
Conclusions: Due to limited testing capacities, mortality numbers may serve as a better indicator for COVID-19 case spread in many countries. Our data indicate that countries like France,
Italy, the United States, Iran and Spain have extremely high numbers of undetected and underreported cases. Differences in testing availability and capacity, containment as well as overall
health care and medical infrastructure result in significantly different mortality rates and
COVID-19 case numbers for each respective country
Palabras clave
Pandemic; Death; Rate; Mortality; COVID-19; SpreadLink para o recurso
https://doi.org/10.1016/j.pulmoe.2020.05.015Collections
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