COVID-19 infection recurrence presenting with meningoencephalitis
Date
2020Author
Mardani, M.
Alireza Nadji, S.
Aghazadeh Sarhangipor, K.
Sharifi-Razavi, A.
Baziboroun, M.
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Abstract
Coronavirus disease 2019 (COVID-19) infection can involve many
organs, such as central nervous system, including in relapse. We
describe the case of a 64-year-old woman with microbiologically
confirmed COVID-19–induced respiratory distress whose
treatment resulted in a negative nasopharyngeal swab reverse
transcriptase PCR (RT-PCR) result for COVID-19. However,
after a few weeks, relapse occurred, as indicated by symptoms of
acute meningoencephalitis. Results of COVID-19 RT-PCR testing
from her cerebrospinal fluid, nasopharyngeal and tracheal
aspiration specimens became positive again, but COVID-19
serum antibodies were negative. We therefore note that
symptoms with neurologic involvement can be one of COVID19’s first presentations, or they can appear at relapse. Regular
evaluation of patients during convalescence is therefore necessary.
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https://doi.org/10.1016/j.nmni.2020.100732Collections
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