Show simple item record

dc.creatorDingens, Adam S
dc.creatorCrawford, Katharine Hd
dc.creatorAdler, Amanda
dc.creatorSteele, Sarah L
dc.creatorLacombe, Kirsten
dc.creatorEguia, Rachel
dc.creatorAmanat, Fatima
dc.creatorWalls, Alexandra C
dc.creatorWolf, Caitlin R
dc.creatorMurphy, Michael
dc.creatorPettie, Deleah
dc.creatorCarter, Lauren
dc.creatorQin, Xuan
dc.creatorKing, Neil P
dc.creatorVeesler, David
dc.creatorKrammer, Florian
dc.creatorChu, Helen Y
dc.creatorEnglund, Janet A
dc.creatorBloom, Jesse D
dc.date.accessioned2020-09-18T03:33:40Z
dc.date.available2020-09-18T03:33:40Z
dc.date.created2020-09-01
dc.identifier.issn2041-1723spa
dc.identifier.otherhttps://www.nature.com/articles/s41467-020-18178-1spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/13443
dc.format.extent6 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherNature Communicationsspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCOVID-19spa
dc.titleSerological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreakspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAbierto (Texto Completo)spa
dc.subject.keywordSerological identificationspa
dc.identifier.doihttps://doi.org/10.1038/s41467-020-18178-1spa
dc.description.abstractenglishChildren are strikingly underrepresented in COVID-19 case counts. In the United States, children represent 22% of the population but only 1.7% of confirmed SARS-CoV-2 cases as of April 2, 2020. One possibility is that symptom-based viral testing is less likely to identify infected children, since they often experience milder disease than adults. Here, to better assess the frequency of pediatric SARS-CoV-2 infection, we serologically screen 1,775 residual samples from Seattle Children’s Hospital collected from 1,076 children seeking medical care during March and April of 2020. Only one child was seropositive in March, but seven were seropositive in April for a period seroprevalence of ≈1%. Most seropositive children (6/8) were not suspected of having had COVID-19. The sera of seropositive children have neutralizing activity, including one that neutralized at a dilution > 1:18,000. Therefore, an increasing number of children seeking medical care were infected by SARS-CoV-2 during the early Seattle outbreak despite few positive viral tests.spa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record