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dc.creatorMehlotra, Rajeev K.
dc.date.accessioned2020-09-07T16:32:33Z
dc.date.available2020-09-07T16:32:33Z
dc.date.created2020
dc.identifier.issn1567-1348spa
dc.identifier.otherhttps://doi.org/10.1016/j.meegid.2020.104512spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/12838
dc.description.abstractEmerging results indicate that an uncontrolled host immune response, leading to a life-threatening condition called cytokine release syndrome (also termed “cytokine storm”), is the major driver of pathology in severe COVID-19. In this pandemic, considerable effort is being focused on identifying host genomic factors that increase susceptibility or resistance to the complications of COVID-19 and translating these findings to improved patient care. In this regard, the chemokine receptor-ligand nexus has been reported as potentially important in severe COVID-19 disease pathogenesis and its treatment. Valuable genomic insights into the chemokine receptor-ligand nexus have been gained from HIV infection and disease progression studies. Applying that knowledge, together with newly discovered potential host genomic factors associated with COVID-19, may lead to a more comprehensive understanding of the pathogenesis and treatment outcomes in COVID-19 patients.spa
dc.format.extent5 páginasspa
dc.format.mimetypeimage/jepgspa
dc.language.isoengspa
dc.publisherInfection, Genetics and Evolutionspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCCR5spa
dc.subjectCOVID-19spa
dc.subjectHIV/AIDSspa
dc.subjectHost geneticsspa
dc.titleChemokine receptor gene polymorphisms and COVID-19: Could knowledge gained from HIV/AIDS be important?spa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAcceso restringidospa
dc.identifier.doihttps://doi.org/10.1016/j.meegid.2020.104512spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa


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