Mostrar el registro sencillo del documento

dc.creatorSuchomel, Miranda
dc.creatorSteinmann, Jochen
dc.creatorKampf, Günter
dc.date.accessioned2020-08-31T20:41:06Z
dc.date.available2020-08-31T20:41:06Z
dc.date.created2020
dc.identifier.issn0195-6701spa
dc.identifier.otherhttps://doi.org/10.1016/j.jhin.2020.08.006spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/12501
dc.description.abstractThe WHO hand rub formulations have been in use around the world for at least the past ten years. The advent of COVID-19 has further enhanced their use. We reviewed published efficacy data for the original and modified formulations. Only efficacy data according to the European Norms (EN) were found. The bactericidal efficacy of the original formulations was under practical conditions partly insufficient (EN 1500, only effective in 60 s; EN 12791, efficacy too low in 5 min). The 1st modification with higher alcohol concentrations improves their efficacy as hygienic hand rub (effective in 30 s). The 2nd (0.725% glycerol) and 3rd (0.5% glycerol) modification improves their efficacy for surgical hand preparation (effective in 5 and 3 min). The original and 2nd modified formulations were tested and demonstrate activity against enveloped viruses including SARS-CoV-2 in 30 s. The ethanol-based formulation is also active against some non-enveloped test viruses in 60 s (suspension tests, EN 14476). In vivo data of the formulations would provide a more reliable result on the virucidal efficacy on contaminated hands but are currently not available. Nevertheless, the last modifications should be adopted for use in healthcare.spa
dc.format.extent20 páginasspa
dc.format.mimetypeimage/jepgspa
dc.language.isoengspa
dc.publisherJournal of Hospital Infectionspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectWHO-recommended hand rubspa
dc.subjectEfficacyspa
dc.subjectModified formulationspa
dc.subjectGlycerolspa
dc.titleEfficacies of the original and modified WHO-recommended hand rub formulationsspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAcceso restringidospa
dc.identifier.doihttps://doi.org/10.1016/j.jhin.2020.08.006spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa


Archivos en el documento

Thumbnail
Thumbnail

Este documento aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del documento