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dc.creatorO’Hearn, Katie
dc.creatorGertsman, Shira
dc.creatorWebster, Richard
dc.creatorTsampalieros, Anne
dc.creatorNg, Rhiannon
dc.creatorGibson, Jess
dc.creatorSampson, Margaret
dc.creatorSikora, Lindsey
dc.creatorDayre McNally, James
dc.date.accessioned2020-08-31T20:36:14Z
dc.date.available2020-08-31T20:36:14Z
dc.date.created2020
dc.identifier.issn0195-6701spa
dc.identifier.otherhttps://doi.org/10.1016/j.jhin.2020.08.005spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/12500
dc.description.abstractBackground: Decontaminating and re-using filtering facepiece respirators (FFRs) for healthcare workers is a potential solution to address inadequate FFR supply during a global pandemic. Aim: The objective of this review was to synthesize existing data on the effectiveness and safety of using chemical disinfectants to decontaminate N95 FFRs. Methods: We conducted a systematic review on disinfectants to decontaminate N95 FFRs using Embase, Medline, Global Health, Google Scholar, WHO feed, and MedRxiv. Two reviewers independently determined study eligibility and extracted predefined data fields. Original research reporting on N95 FFR function, decontamination, safety, or FFR fit following decontamination with a disinfectant was included. Findings and Conclusions: A single cycle of vaporized hydrogen peroxide (H2O2) successfully removes viral pathogens without affecting airflow resistance or fit, and maintains an initial filter penetration of <5%, with little change in FFR appearance. Residual hydrogen peroxide levels following decontamination were within safe limits. More than one decontamination cycle of vaporized H2O2 may be possible but further information is required on how multiple cycles would affect FFR fit in a real world setting before the upper limit can be established. Although immersion in liquid H2O2 does not appear to adversely affect FFR function, there is no available data on its ability to remove infectious pathogens from FFRs or its impact on FFR fit. Sodium hypochlorite, ethanol, isopropyl alcohol and ethylene oxide are not recommended due to safety concerns or negative effects on FFR function.spa
dc.format.extent46 páginasspa
dc.format.mimetypeimage/jepgspa
dc.language.isoengspa
dc.publisherJournal of Hospital Infectionspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectPPEspa
dc.subjectDecontaminationspa
dc.subjectRespiratorspa
dc.subjectN95spa
dc.subjectDisinfectantsspa
dc.subjectCOVID-19spa
dc.subjectPandemicspa
dc.subjectFFRspa
dc.titleEfficacy and safety of disinfectants for decontamination of N95 and sn95 filtering facepiece respirators: a Systematic reviewspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAcceso restringidospa
dc.identifier.doihttps://doi.org/10.1016/j.jhin.2020.08.005spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa


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