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dc.creatorSong, Wenliang
dc.creatorLi, Junhua
dc.creatorZou, Ning
dc.creatorGuan, Wenhe
dc.creatorPan, Jiali
dc.creatorXu, Wei
dc.date.accessioned2020-08-31T17:04:15Z
dc.date.available2020-08-31T17:04:15Z
dc.date.created2020-06
dc.identifier.issn1386-6532spa
dc.identifier.otherhttps://www.sciencedirect.com/science/article/pii/S1386653220301190spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/12472
dc.format.extent7 Páginaspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherJournal of Clinical Virologyspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCOVID-19spa
dc.titleClinical features of pediatric patients with coronavirus disease (COVID-19)spa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAcceso restringidospa
dc.subject.keywordNovel coronavirus disease (COVID-19)spa
dc.subject.keywordSARS-CoV-2spa
dc.subject.keywordChildrenspa
dc.identifier.doihttps://doi.org/10.1016/j.jcv.2020.104377spa
dc.description.abstractenglishBackground Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has spread around the world, and reports of children with COVID-19 are increasing. Objectives To assess clinical profiles of pediatric COVID-19. Study design A retrospective analysis was undertaken using clinical data of sixteen children (11 months-14 years) diagnosed with COVID-19 between January 1, 2020 and March 17, 2020 at Xiangyang Central Hospital, Hubei province, China. Results All children had positive epidemiologic histories, 12 (12/16, 75 %) involving family units. The illnesses were either mild (5/16, 31.3 %) or ordinary (11/16, 68.8 %), presenting as follows: asymptomatic (8/16, 50 %), fever and/or cough (8/16, 50 %). Four asymptomatic patients (4/16, 25 %) in ordinary cases had chest computed tomography (CT) abnormalities. Leukocyte counts were normal in 14 cases(88 %), but 2 patients (12.5 %) had leukopenia, and 1 (6.3 %) was lymphopenic. There were 11 patients with chest CT abnormalities, some nodular, others small patchy and others ground-glass opacities. In asymptomatic children, the median time to SRAS-CoV-2 nucleic acid test(NAT) positivity once exposed to a family member with confirmed infection was 15.5 days (range, 10–26 days). The median time to first NAT-negative conversion was 5.5 days (range, 1–23 days). Conclusions COVID-19 in children of Xiangyang city is often family acquired and not serious, with favorable outcomes. Asymptomatic children can be diagnosed as pneumonia because of chest CT abnormalities. It is essential to actively screen this segment of the population.spa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa


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