• español
    • English
    • português
  • English 
    • español
    • English
    • português
  • Login
View Item 
  •   Home
  • Productos de Investigación - Creación
  • Repositorio Documental COVID-19
  • Documentos científicos relacionados a la COVID-19
  • View Item
  •   Home
  • Productos de Investigación - Creación
  • Repositorio Documental COVID-19
  • Documentos científicos relacionados a la COVID-19
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.
JavaScript esta deshabilitado en su navegador. Algunas características de este sitio no podrán funcionar o visualizarse correctamente sin JavaScript.
RecursosRecursos de apoyo¿Cómo publicar?

Browse

All of ExpeditioCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

View Usage StatisticsView Google Analytics Statistics
Estadísticas GTMVer Estadísticas GTM

The under-reported role of toxic substance exposures in the COVID-19 pandemic

Thumbnail

Citación

       
Export: <XML METS>
View/Open
Ver portada (82.98Kb)
Fin embargo: 
Artículo reservado (776.6Kb)
Fin embargo: 
Date
2020
Author
Kostoff, Ronald N.
Briggs, Michael B.
Porter, Alan L.
Hernández, Antonio F.
Abdollahi, Mohammad
Aschner, Michael
Tsatsakis, Aristidis
Metadata
Show full item record
Documentos PDF
Imagenes y Videos
Captura.PNG

Abstract
Coronavirus disease 2019 (COVID-19) and previous pandemics have been viewed almost exclusively as virology problems, with toxicology problems mostly being ignored. This perspective is not supported by the evolution of COVID-19, where the impact of real-life exposures to multiple toxic stressors degrading the immune system is followed by the SARS-CoV-2 virus exploiting the degraded immune system to trigger a chain of events ultimately leading to COVID-19. This immune system degradation from multiple toxic stressors (chemical, physical, biological, psychosocial stressors) means that attribution of serious consequences from COVID-19 should be made to the virus-toxic stressors nexus, not to any of the nexus constituents in isolation. The leading toxic stressors (identified in this study as contributing to COVID-19) are pervasive, contributing to myriad chronic diseases as well as immune system degradation. They increase the likelihood for comorbidities and mortality associated with COVID-19. For the short-term, tactical/reactive virology-focused treatments are of higher priority than strategic/proactive toxicology-focused treatments, although both could be implemented in parallel to reinforce each other. However, for long-term pandemic prevention, toxicology-based approaches should be given higher priority than virology-based approaches. Since current COVID-19 treatments globally ignore the toxicology component almost completely, only limited benefits can be expected from these treatments.
URI
http://hdl.handle.net/20.500.12010/12457
Link to resource
https://doi.org/10.1016/j.fct.2020.111687
Collections
  • Documentos científicos relacionados a la COVID-19 [2292]
Estadísticas Google Analytics
Comments

Respuesta Comentario Repositorio Expeditio

Gracias por tomarse el tiempo para darnos su opinión.


Carrera 4 # 22-61 Teléfono: (+57 1) 242 7030 - 018000111022 Fax: (+57 1) 561 2107 Bogotá D.C., Colombia

Fundación Universitaria de Bogotá Jorge Tadeo Lozano | Vigilada Mineducación

Institución de educación superior privada, de utilidad común, sin ánimo de lucro y su carácter académico es el de Universidad.

Reconocimiento personería jurídica: Resolución 2613 del 14 de agosto de 1959 Minjusticia.

Institución de Educación Superior sujeta a inspección y vigilancia por el Ministerio de Educación Nacional.

 

Términos y condiciones | Políticas

 

 


Carrera 4 # 22-61 Teléfono: (+57 1) 242 7030 - 018000111022 Fax: (+57 1) 561 2107 Bogotá D.C., Colombia

Fundación Universitaria de Bogotá Jorge Tadeo Lozano | Vigilada Mineducación

Institución de educación superior privada, de utilidad común, sin ánimo de lucro y su carácter académico es el de Universidad.

Reconocimiento personería jurídica: Resolución 2613 del 14 de agosto de 1959 Minjusticia.

Institución de Educación Superior sujeta a inspección y vigilancia por el Ministerio de Educación Nacional.

 

Términos y condiciones | Políticas