Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: could they help against COVID-19?
Fecha
2020Autor
Shakoor, Hira
Feehan, Jack
Al Dhaheri, Ayesha S
Ali, Habiba I
Platat, Carine
Cheikh Ismail, Leila
Apostolopoulos, Vasso
Stojanovska, Lily
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Resumen
The world is currently in the grips of the coronavirus disease (COVID-19) pandemic, caused
by the SARS-CoV-2 virus, which has mutated to allow human-to-human spread. Infection can
cause fever, dry cough, fatigue, severe pneumonia, respiratory distress syndrome and in some
instances death. COVID-19 affects the immune system by producing a systemic inflammatory
response, or cytokine release syndrome. Patients with COVID-19 have shown a high level of
pro-inflammatory cytokines and chemokines. There are currently no effective anti-SARSCoV-2 viral drugs or vaccines. COVID-19 disproportionately affects the elderly, both directly,
and through a number of significant age-related comorbidities. Undoubtedly, nutrition is a key
determinant of maintaining good health. Key dietary components such as vitamins C, D, E,
zinc, selenium and the omega 3 fatty acids have well-established immunomodulatory effects,
with benefits in infectious disease. Some of these nutrients have also been shown to have a
potential role in the management of COVID-19. In this paper, evidence surrounding the role
of these dietary components in immunity as well as their specific effect in COVID-19 patients
are discussed. In addition, how supplementation of these nutrients may be used as therapeutic
modalities potentially to decrease the morbidity and mortality rates of patients with COVID19 is discussed.
Enlace al recurso
https://doi.org/10.1016/j.maturitas.2020.08.003Colecciones
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