Show simple item record

dc.creatorZhang, Dong
dc.creatorMa, Zhi
dc.creatorChen, Hanchi
dc.creatorLu, Yuele
dc.creatorChen, Xiaolong
dc.date.accessioned2020-08-12T15:01:13Z
dc.date.available2020-08-12T15:01:13Z
dc.date.created2020
dc.identifier.issn2319-4170spa
dc.identifier.otherhttps://doi.org/10.1016/j.bj.2020.08.006spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/11863
dc.description.abstractHuman coronaviruses (HCoVs), including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have been resulting in global epidemics with heavy morbidity and mortality. Unfortunately, there are currently no specific medicines that can better treat these coronaviruses. Drug repurposing is an effective and economical strategy for drug discovery from existing drugs, natural products, and synthetic compounds. In this review, the broad-spectrum antiviral activity of valinomycin (VAL), especially its activity against coronaviruses such as SARS-CoV, MERS-CoV, human coronavirus OC43 (HCoV-OC43), were summarized, it highlights that VAL has tremendous potential for use as a novel antiviral agent against SARS-CoV-2.spa
dc.format.extent30 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.publisherBiomedical Journalspa
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCoronavirusspa
dc.subjectSARS-CoV-2spa
dc.subjectDrug repurposingspa
dc.subjectValinomycinspa
dc.subjectAntiviral agentspa
dc.titleValinomycin as a potential antiviral agent against coronaviruses: a reviewspa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rights.localAbierto (Texto Completo)spa
dc.identifier.doihttps://doi.org/10.1016/j.bj.2020.08.006spa


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record