Genetic comparison among various coronavirus strains for the identification of potential vaccine targets of SARS-CoV2
Date
2020Author
Kaur, Navpreet
Singh, Rimaljot
Dar, Zahid
Kumar Bijarnia, Rakesh
Dhingra, Neelima
Kaur, Tanzeer
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Abstract
On-going pandemic pneumonia outbreak COVID-19 has raised an urgent public health issue
worldwide impacting millions of people with a continuous increase in both morbidity and
mortality. The causative agent of this disease is identified and named as SARS-CoV2 because of
its genetic relatedness to SARS-CoV species that was responsible for the 2003 coronavirus
outbreak. The immense spread of the disease in a very small period demands urgent development
of therapeutic and prophylactic interventions for the treatment of SARS-CoV2 infected patients.
A plethora of research is being conducted globally on this novel coronavirus strain to gain
knowledge about its origin, evolutionary history, and phylogeny. This review is an effort to ompare genetic similarities and diversifications among coronavirus strains, which can hint
towards the susceptible antigen targets of SARS-CoV2 to come up with the potential therapeutic
and prophylactic interventions for the prevention of this public threat.
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https://doi.org/10.1016/j.meegid.2020.104490Collections
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