Impact of obesity on hospitalizations and mortality, due to COVID-19: A systematic review
Date
2020Author
Vieira de Siqueira, Joao Vitor
Garrido Almeida, Lucas
Otávio Zica, Bruno
Batista Brum, Ingred
Barcelo, Alberto
Garcia de Siqueira Galil, Arise
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Abstract
The aim of the current review was to assess whether there was an association
between obesity and higher levels of hospitalization, poor outcomes and
mortality due to the disease of novel coronavirus (COVID-19). Methodology: A
systematic review of articles on the novel coronavirus, containing information on
obesity and its association with COVID-19 morbidity and mortality. In the
bibliographic research, four databases were used, with the terms ['COVID-19']
AND ['hospitalization'] AND ['obesity'] AND ['mortality']. Studies published from
12/01/2019 until 05/01/2020 were included. The research contains inclusive
criteria targeting studies of humans adults infected by Sars-Cov-2, with or
without comorbidities. This research was selected from publications in Spanish
and English languages. Results: 96 articles were identified, 15 being presented
in two databases. Twenty articles were included, with a population total
estimated from 1 to 7671 patients, with a prevalence of obesity ranging from
13.3% to 68.6%. The association of obesity and mortality has been observed in
at least 4 studies, that 85.3% of the population was hospitalized. Among 19 of
the 20 studies, more severe forms of the disease were observed and in 14 of
them, higher rates of complications among obese people infected with the new
coronavirus. Limitation differences in the definition of obesity was observed
among publications, of which obesity was considered from a body mass index
>25kg/m². Conclusions: In the current review, obesity and overweight were
represented an unfavorable factor for infection of novel coronavirus, where the
higher the BMI the worse the outcomes. This occurred by worsening the
infection itself, as well as increasing the prevalence of hospitalizations, worst
outcomes and greater lethality; especially when co-occurring with other chronic
conditions and in the elderly as well. Given this evidence, greater attention is
suggested to the obese and overweight population in the face of the current
pandemic.
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https://doi.org/10.1016/j.orcp.2020.07.005Collections
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