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dc.creatorLuo, Pan
dc.creatorLiu, Dong
dc.creatorLi, Juan
dc.date.accessioned2020-07-31T20:10:52Z
dc.date.available2020-07-31T20:10:52Z
dc.date.created2020
dc.identifier.issn0924-8579spa
dc.identifier.otherhttps://doi.org/10.1016/j.ijantimicag.2020.105995spa
dc.identifier.urihttp://hdl.handle.net/20.500.12010/11493
dc.description.abstractCoronavirus disease 2019 (COVID-19) caused by the previously unknown pathogen, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is now a global pandemic. There are no vaccines or specific treatments against this new virus; therefore, there is an urgent need to advance novel therapeutic interventions for COVID-19. Glycyrrhizin is a triterpene saponin with various biological functions and pharmacological effects. This brief article discusses the therapeutic potential of glycyrrhizin for the treatment of COVID-19 from the perspective of its pharmacological action, including binding angiotensinconverting enzyme II (ACE2), downregulating proinflammatory cytokines, inhibiting the accumulation of intracellular reactive oxygen species (ROS), inhibiting thrombin, inhibiting the hyperproduction of airway exudates, and inducing endogenous interferon.spa
dc.format.extent3 páginasspa
dc.format.mimetypeimage/jepgspa
dc.publisherScience Directeng
dc.sourcereponame:Expeditio Repositorio Institucional UJTLspa
dc.sourceinstname:Universidad de Bogotá Jorge Tadeo Lozanospa
dc.subjectCOVID-19spa
dc.subjectSARS-COV-2spa
dc.subjectGlycyrrhizinspa
dc.titlePharmacological perspective: glycyrrhizin may be an efficacious therapeutic agent for COVID-19spa
dc.type.localArtículospa
dc.subject.lembSíndrome respiratorio agudo gravespa
dc.subject.lembCOVID-19spa
dc.subject.lembSARS-CoV-2spa
dc.subject.lembCoronavirusspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.identifier.doihttps://doi.org/10.1016/j.ijantimicag.2020.105995spa


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