Gastrointestinal symptoms and Coronavirus disease 2019: A case-control study from the United States
Nobel, Yael R.
Wang, Timothy C.
Sobieszczyk, Magdalena E.
Freedberg, Daniel E.
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Coronavirus disease 2019 (COVID-19) is a pandemic characterized by a high fatality rate.1 The incidence of COVID-19 has risen dramatically in the United States since March 2020, with the highest number of cases in the country present in New York City.2 As health care systems rise to the challenge of unprecedented demands, there is an urgent need to characterize the spectrum of clinical presentations of this disease to allow early identification, isolation, and triage of affected patients. Although fever, cough, and shortness of breath are among the most common presenting symptoms, gastrointestinal symptoms are increasingly recognized among patients with COVID-19.3–7 This case-control study aimed to describe gastrointestinal symptomatology—including diarrhea and nausea/vomiting—in US patients with COVID-19 compared to patients presenting under similar circumstances who tested negative for COVID-19. The secondary aims were to characterize the associations of gastrointestinal symptoms with total illness duration and early clinical outcomes.
Link to resourcehttps://doi.org/10.1053/j.gastro.2020.04.017
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